目的:了解右美托咪啶对正颌手术全麻苏醒期的影响.方法:40例ASA Ⅰ-Ⅱ级择期行颌面外科正颌手术患者,随机分为右美托咪啶组(D组)和生理盐水组(C组).D组患者术毕前30 rmin给予右美托咪啶0.6 μg/kg,泵注10 min后以0.4μg(kgh)持续泵入.C组患者以相同速率输注生理盐水.在患者清醒(T1),拔管(T2),拔管后20 rmin(T3)行Ramsay评分；在T2记录2组躁动率；在T3行全麻后舒适度(BCS)评分.结果:与C组相比,D组在T1、T2、T3的Ramsay评分明显增加(P＜0.05)；2组在T2躁动率有明显差异(P＜0.05)；D组BCS评分明显高于C组(P＜0.05).结论:术毕前泵入右美托咪啶可明显减少正颌手术患者拔管期躁动程度,并且提高患者带管耐受性.%Objective:To study the effect of dexmedetomidine on the recovery of patients after general anesthesia in orthognathic surgery.Methods:40 patients with ASA Ⅰ-Ⅱ degree jaw deformity undergoing orthognathic surgery were randomly divided into dexmedetomidine group (D) and normal saline group (C) with 20 cases in each.In group D,dexmedetomidine was administered intravenously at 0.4 μg(kg · h) after a bolus infusion at 0.6 μg/kg for 10 min before ending operation.Nornial saline was given by the same way in group C.Ramsay sedation scores were monitored at the time of awaken(T1),immediately after extubation(T2),20 rain after extubation(T3) ;the restlessness assessment was recorded at T2 and the bruggrmann comfort scale(BCS) assessment was recorded at T3.Results:Ramsay sedation scores were higher at T4,T2 and T3 in group D than those in group C (P ＜ 0.05) ; the restlessness in group D was less than in group C at T2 (P ＜ 0.05) ; the BCS was significantly higher in group D than in group C.Conclusion:Dexmedetomidine given before ending operation may decrease the restlessness in patients undergoing orthognathic surgery and improve the tolerance of retaining tracheal catheter.
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