Objective:To explore the effectiveness of endometrial scratching on pregnancy outcome in infertile women undergoing IVF or ICSI.Methods:A total of 142 infertile women enrolled from Jan.2012 to Dec.2014.The patients were randomly divided into intervention group (n =70) and control group (n =72).The patients underwent endometrial scratching in follicular phase or mid-luteal phase before IVF/ICSI-ET in the intervention group,which was not performed in the control group.The general status and the pregnancy outcomes were compared between the two groups.Results:There were no significant differences in age,duration of infertility,infertile causes,body mass index and other general conditions between the two groups (P ＞ 0.05).There were no significant differences in implantation rate(27.2％ vs.26.7％),biochemical pregnancy rate(54.3％ vs.52.8％),clinical pregnancy rate(41.4％ vs.41.7％),miscarriage rate(3.4％ vs.3.3％),multiple pregnancy rate (34.5％ vs.30.0％),andthe live birth rate(35.7％ vs.40.3％)between the two groups(P＞0.05).Conclusions:Once endometrial scratching in follicular or luteal phase before the first IVF/ICSI cycle does not improve the pregnancy outcome in infertile women.%目的 探索子宫内膜搔刮术对首次行IVF/ICSI-ET的不孕女性妊娠结局的影响.方法 分析2012年1月至2014年12月在我院行IVF/ICSI-ET的助孕患者142例,根据随机数字表法,将患者分为干预组(70例)和对照组(72例).干预组于胚胎移植前一周期的卵泡期或黄体期行子宫内膜搔刮,对照组不予任何处理,比较两组患者的一般情况及妊娠结局.结果 两组患者的年龄、不孕年限、不孕原因、体重指数等一般情况均无显著性差异(P均＞0.05).干预组的种植率、生化妊娠率、临床妊娠率、流产率、多胎率及活产率分别为27.2％、54.3％、41.4％、3.4％、34.5％及35.7％,对照组分别为26.7、52.8％、41.7％、3.3％％、30.0％及40.3％,两组间比较无显著性差异(P均＞0.05).结论 在胚胎移植前一周期的卵泡期或黄体期对首次行IVF/ICSI助孕的不孕女性行1次内膜搔刮,并不能改善不孕女性的妊娠结局.
展开▼
