Objective:To detect the effect of embryo quality on pregnancy outcome in vitro fertilization (IVF).rn Methods: Between June 1998 and June 1999,a review of 195 consecutive IVF-embryo transfer (ET)cycles performed in 162 couples was carried out. The mean age, insemination rate, cleavage rate, proportion of the number of blastomeres, embryo morphology, the number of embryo transferred, endometrial thickness, implantation rate and the rate of multiple pregnancy were analyzed.rn Results: Pregnancy rate of embryo transfer cycles was 27.2% (53/195). The implantation rate was 14.7% (91/621). The miscarriage rate was 30.2%(16/53). However, significant difference were found in insemination rate (74.7%∶63.5%; P<0.05), embryo cleavage rate (74.8%∶68.1%; P<0.05), proportion of the number of blastomere (P<0.05), percentage of total number of grade I embryo transferred (60.4%∶43.7%; P<0.05), percentage of at least one grade I embryo transferred (39.6%∶31.7%; P<0.05), the number of embryo transferred(P<0.01) and endometrial thickness (P<0.05) between conception and non-conception cycles. Therern 作者单位：广州医学院附属市二医院妇科研究室，广州 510150rnwas no significant dif-ference in all of these parametric rate, between the miscarriage group and the ongoingpregnancy/live birth group. The significant differences in the rate of multiple pregnancy were noted.rn Conclusion: embryo morphology can be taken as a parameter to evaluate embyo quality, but embryo quality has no effect on the pregnancy outcome once clinical pregnancy is established.%目的：探讨胚胎质量对体外受精(IVF)妊娠结局的影响。方法：对1998年6月～1999年6月间的162对夫妇，195个周期的平均年龄、卵裂率、卵裂球构成比、胚胎形态、移植胚胎数、内膜厚度、种植率及多胎妊娠率进行了分析。结果：妊娠周期与非妊娠周期的平均年龄无显著性差异(P>0.05)；胚胎受精率(74.7%∶63.5%)、卵裂率(74.8%∶68.1%)、全部I级胚胎移植数(60.4%∶43.7%)、至少1个I级胚胎移植数(39.6%∶31.7%)有显著性差异(P<0.05)，卵裂球数构成比、移植胚胎数均有极显著性差异(P<0．01)；内膜厚度有显著性差异(P<0.05)。而正在妊娠/活婴组与流产组上述各项指标均无显著性差异(P>0.05)，仅不同I级胚胎移植数的多胎妊娠率有非常显著的差异(P<0.005)。结论：根据本实验室结果认为，形态学可作为评定胚胎质量的参数，但一旦临床妊娠，根据形态学评定的胚胎质量并不影响妊娠的结局。I级胚胎移植数与多胎妊娠的发生密切相关。
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