Objective To assess the value of contrast-enhanced ultrasonography (CEUS) and fluorodeoxyglucose positron emission tomography-computed tomography ("F-FDG PET/CT) in evaluating the stability of carotid atherosclerosis. Methods Seventeen patients with 21 carotid artery plaques received examinations with CEUS. According to the nature of the plaques, the patients were divided into soft and mixed plaque group and hard and calcified plaque group. The maximal enhancement intensity of the plaques (IMAX) and maximal plaque density (DMAX) were measured to quantify the neovasculature. The patients also underwent concurrent "F-FDG PET/CT, and 18F-FDG uptake was quantified by the mean standard uptake values (SUVmean), an index reflecting the inflammatory activity in the plaque. The findings in CEUS and PET/CT were comparatively analyzed for these cases. Results The DMAX of the plaque in soft and mixed plaque group was significantly greater than that in hard and calcined plaque group (4.26±3.65 vs 1.41±1.47, P<0.05); the IMAX was also greater in the former group, but this difference was not statistically significant (26.83±19.61 vs 24.73±29.85, P=0.869). The soft and mixed plaques tended to have higher SUVmean, than the hard and calcified plaques (170±0.45 vs 1.47±0.12, P=0.099). The values of W and DMAX were not found to correlate to SUVmean in these patients. Conclusion CEUS can sensitively show the status of neovascularization within the carotid atherosclerosis plaques, and PET/CT reflects the inflammatory activity in the plaques. The combination of these two imaging modalities allows the evaluation of plaque stability in terms of neoangiogenesis and inflammatory activity.%目的 应用超声造影技术评价颈动脉粥样硬化斑块内血管新生,应用PET/CT技术评价颈动脉粥样硬化斑块内巨噬细胞炎症活性,整体评估颈动脉粥样硬化斑块的稳定性.方法 运用超声造影技术对17例颈动脉粥样硬化患者的21个斑块进行斑块内新生血管检测,根据斑块性质分为软斑+混合斑组(14个)和硬斑+钙化斑组(7个),比较组间斑块相对管腔的最大增强强度(IMAX)及最大增强密度(DMAX).同期行颈部PET/CT检查,比较组间相应位置颤动脉斑块处反映18F-FDG摄取的平均标准化摄取值(SUVmean).并对超声造影与PET/CT的检查结果进行对比分析.结果 软斑+混合斑组颈动脉粥样硬化斑块的DMAX值(4.26±3.65)明显高下硬斑+钙化斑组(1.41±1.47)(P＜0.05).软斑+混合斑组颈动脉粥样硬化斑块内的IMAX值(26.83±19.61)高于硬斑+钙化斑组(24.73±29.85),软斑+混合斑组颈动脉粥样硬化PET/CT检查的SUVmean值(1.70±0.45)高于硬斑+钙化斑组(1 47±0.12),但无统计学差异.超声造影的IMAX、DMAX结果与PET的定量指标SUVmean间无关联(P＞0.05).结论 超声造影可以敏感地显示斑块内新生血管的增强情况,PET/CT可以显示颈内动脉粥样硬化斑块炎症程度,两种影像技术可以从不同角度观察和评价斑块的稳定性.
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机译：Tecnologie Gsm，WiFi e DECT in ambiente Ospedaliero：Valutazione della Compatibilita elettromagnetica con Dispositivi medici di supporto Vitale。 （医院的Gsm，WiFi和DECT技术：评估与生命支持设备的电磁兼容性）
