Objective To investigate influential factors and clinical significance of serum sodium reduction in children with febrile convulsion. Methods To analyze retrospectively the serum sodium concentration changes in children with febrile convulsion.Results In 236 cases,girls (90/236) serum sodium values for (135.97 ±3.04) mmol/L,boys(146/236) serum sodium values for (134.55±3.57) mmol/L,P=0.002,31.11% of the girls (28/90) had lower serum sodium,54.11% of the boy (79/146) had lower serum sodium,χ2=11.883,P=0.001;twitching time ranging from 30 seconds to 20 minutes,3 minutes,5 minutes and 10 minutes respectively grouped boundaries,in dif erent groups of children serum sodium statistics P>0.05;serum sodium and serum sodium reduction rate was no significant statistical dif erence between children with previous twitching history (89/236) and no twitching history (147/236);in children with having family history (78/236) and no family history (158/236),serum sodium and serum sodium reduction rate was no significant statistical dif erence.Conclusion In children with febrile convulsion,there is often decreased serum sodium,the proportion of reduction with serum sodium is higher in male children;and there is no clear correlation with twitching time,twitching history,family history.%目的：探讨高热惊厥(Fc)患儿发生血清钠降低的影响因素及其临床意义。方法对236例高热惊厥患儿血清钠浓度变化进行回顾分析。结果236病例中，女童(90/236)血钠值为(135.97±3.04) mmol/L，男童(146/236)血钠值为(134.55±3.57) mmol/L, P=0.002，女童中31.11%(28/90)有血清钠降低，男童中54.11%(79/146)有血清钠降低，χ2=11.883，P=0.001；抽搐时间在30s~20min不等，分别以3min、5min及10min为分组界限，不同组别的患儿血清钠统计 P＞0.05；既往有抽搐史者(89/236)与无抽搐史者(147/236)血钠值及血钠降低率统计学差异无显著意义；有家族史者(78/236)与无家族史(158/236)血钠值及血钠降低率统计学差异无显著意义。结论发生热性惊厥的患儿中，常存在血清钠下降，其中男性患儿发生血清钠降低比例更高；并与抽搐时间、抽搐史、家族史无明确相关。
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