CD+4 CD+25 regulatory cell( Treg) is one of an important immune supression cells among discoverable immune cells, which almost suppress all immune reaction and take negative regulatory function.Dendritic cell( DC)is one of full-time antigen presenting cell,which conducts its function in antigen recongnition and presantation, posses double characteristics in starting immune reaction and induing mimune tolerance,and also play key role in anti-hepatitis B virus( HBV).As two important cells Treg and DC in the pathogensis of HBV infection,approaching the cross-talk between them might provide new method for treatment HBV.%CD4 +CD25 +调节性T细胞(Treg)是迄今为止所发现的最重要的免疫抑制细胞,几乎抑制所有的免疫反应,在机体免疫系统中发挥负向调节作用.树突状细胞(DC)作为一类专职的抗原递呈细胞,在抗原识别、递呈中发挥重要作用,具有启动免疫应答和诱导免疫耐受的双重特性,对机体抗乙型肝炎病毒(HBV)起关键作用.作为在HBV致病机制中起重要作用的两个免疫细胞群--Treg与DC,探讨二者在慢性乙型肝炎发病机制中的相互作用,必将为进一步探索治疗HBV提供新的思路.
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