Objective To evaluate the efficacy of transforaminal lumbar interbody fusion combining contralateral percutaneous pedicle screw for degenerative lumbar disc herniation by Wiltse approach. Methods We studied 40 patients affected by lumbar disc herniation underwent transforaminal lumbar interbody fusion combining contralateral percutaneous pedicle screw ifxation by Wiltse approach in our hospital from June 2009 until December 2012 retrospectively. Clinical and radiographic evaluation were carried out preoperatively and following surgery. Clinical outcome was assessed using the Visual Analog Scale scores (VAS) and The Japanese Orthopaedic Association (JOA) scores. Results The average follow-up time was fourteen months, the average blood loss was three hundreds twenty-six milliliter, the difference of postoperative VAS score and JOA score comparing with preoperative was statistically significant(P<0.01). All screws showed very good position by photos. Bone fusion was considered as solid in forty patients at postoperative 12 months (100%). Conclusion Transforaminal lumbar interbody fusion using percutaneous pedicle screw ifxation by Wiltse approach is a valid and safe treatment of degenerative lumbar disc herniation.%目的：评估Wiltse 入路（后旁正中入路）经椎间孔椎间融合结合对侧经皮椎弓根螺钉治疗退变性腰间盘突出的有效性。方法回顾性研究2009年6月至2012年12月应用Wiltse 入路经椎间孔椎间融合结合对侧经皮椎弓根螺钉固定治疗的40例腰椎间盘突出患者，术前术后进行临床及影像学评估，临床结果应用疼痛模拟视觉评分（VAS）、日本骨科协会（JOA）评分进行评估。结果患者平均随访14个月，平均失血326 mL，术后VAS评分、JOA评分较术前比较差异具有统计学意义（P<0.01），影像学显示所有椎弓根螺钉位置良好，术后12个月40例患者获得良好的融合（100%）。结论Wiltse入路经椎间孔椎间融合结合对侧经皮椎弓根螺钉固定技术是治疗退变性腰间盘突出的安全而有效的治疗方法。
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