PET and SPECT is the most advanced nuclear medical imaging technology .GATE is a dedicated Monte Carlo simulation platform for PET and SPECT .This study validates two GATE models of Simens ECAT EXACT HR+PET scanner and Simens PET/CT Biograph 2.After the simulation of PET systems completed , testing and performance evaluation of simulation systems were proceeded according to NEMA 2001 performance protocols , including spatial resolution , scatter fraction and sensitivity .Test results show that , performances of GATE simulation systems agree well with the experimental values .%PET和SPECT是现代核医学最高水平的影像技术，GATE是专用于PET和SPECT的蒙特卡罗仿真工具。研究以西门子公司的PET扫描仪 ECAT EXACT HR＋和PET/CT Biograph2为原型，分别使用GATE实现其系统的完整仿真。依据NEMA 2001标准，对仿真系统的空间分辨率、散射分数和灵敏度分别进行测试与评估。测试结果表明，仿真系统性能参数和实验结果之间具有良好的一致性。
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