目的：探讨结肠镜在诊断结肠息肉癌变中的作用及结肠息肉癌变的相关因素。方法选择经结肠镜检查发现结肠息肉并行病理检查的220例患者，回顾性分析结肠镜下癌变部位、大小、数目及病理类型，并分析患者性别、年龄及息肉部位、大小、数目、形态、病理类型与癌变的相关性。结果不同性别患者结肠息肉癌变率无统计学意义。结肠息肉癌变与年龄、息肉部位、直径大小、数目、形态、病理类型有关。多因素分析显示年龄≥60岁的患者，息肉位于直肠和乙状结肠、直径＞2．0 cm、多发、病理类型为腺瘤性尤其是绒毛状腺瘤性是发生癌变的高危因素。结论结肠镜在诊断结肠息肉癌变患者中具有重要作用，应密切随访，及时切除，降低结肠癌发病率及死亡率。%Objective To investigate the role of endoscopy in the diagnosis of carcinogenesis of colorectal polyps and in -fluencing factors .Methods 220 patients who received endoscopy and pathologic examination and diagnosed as colorectal polyps were enrolled in this study .The position,size,number,pathologic type of polyp carcinoma under colonoscopy were retrospectively analyzed,and the correlation between patients ’ gender,age,clinical symptoms,and the position,size,number,shape,pathologic type of polyps and polyp-carcinoma were analyzed .Results There was no significant difference in canceration rate between male and female patients.Carcinogenesis of colorectal polyps was related with patients ’age,and position,size,number,shape and path-ologic type of polyps.Multivariate analysis indicated that patients ≥60 years old,and diameter >2 cm,multiple,villous adenoma in rectum and sigmoid colon were high risk factors of canceration .Conclusion Endoscopy plays an important role in the diagno-sis of carcinogenesis of colorectal polyps ,which should be followed up closely and receive operation in time to reduce occurrence and mortaliy of colorectal cancer .
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