首页> 中文期刊> 《自然科学进展(英文版)》 >Effects of collagen types II and X on the kinetics of crystallization of calcium phosphate in biomineralization

Effects of collagen types II and X on the kinetics of crystallization of calcium phosphate in biomineralization

         

摘要

<正> The effects of the components of cartilages matrix on the process of endochondral ossification and the kinetics of crystal growth of calcium phosphate have been studied in the presence of type II or X collagen. During the experiments, type I collagen was added as the seed material. FT-IR analysis shows that calcium phosphate crystallized on the surface of type I collagen was mainly hydroxyapatite. Both type II and X collagens could reduce the growth rate of calcium phosphate crystals, and the effect of type X collagen is more obvious. The reaction was in the fourth order in the presence of type II collagen. The results showed that type II or X collagen had the ability to make Ca2+ accumulate in the process of endochondral ossification, but has little effect on crystal growth and the product of biomineraliza-tion.

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