首页> 中文期刊> 《动物医学进展》 >抗 PRRSV 和 PCV-2-Cap 蛋白特异性 IgY 抗体对保育猪生长和免疫的影响

抗 PRRSV 和 PCV-2-Cap 蛋白特异性 IgY 抗体对保育猪生长和免疫的影响

         

摘要

Weaning piglets were fed with specific egg yolk immunoglobulin (IgY)antibodies against porcine reproductive and respiratory syndrome virus (PRRSV)and porcine circovirus type 2(PCV-2)-Cap protein, of which on growth performance and immunity was investigated.The results indicated that PRRSV and PCV-2 antibody negative rate was higher 15% and 5% in 0.5% groups than that of in blank groups at 53 days of age,respectively.Compared with blank groups,S/P average value of positive PRRSV antibody ti-ter in 0.5% groups decreased 15.59% and 24.53% over 53 and 60 days of age,respectively.During 46 to 60 days of age,SP average value of postive PCV-2 antibody titer of 0.5% groups were lower 15.42%, 19.66%and 12.70% than that of in blank groups,respectively.Compared with blank groups,finial body weight,daily weight gain and survival rate of 0.5% groups were improved 12.74% (P < 0.01),16.90%(P < 0.01)and 1.67% at weaning piglets,respectively.The expressions of PRRSV antigen in 0.5%groups were abolished in jejunum and small intestine with immunohistochemistry analysing,compared with the blank groups.The special IgY additive could provide a novel alternative approach to prevent and control diseases caused by PRRSV and PCV-2 infection in pigs.%应用特异性抗猪繁殖与呼吸综合征病毒(PRRSV)和猪圆环病毒2型(PCV-2)Cap 蛋白卵黄免疫球蛋白(IgY)饲喂保育猪,观察其对保育猪生长和免疫性能的影响。经抗体检测表明,53日龄时,PRRSV和 PCV-2抗体阴性率0.5%,试验组比对照组分别高15%和5%。在53日龄和60日龄时,保育猪 PRRSV阳性抗体 S/P 均值,试验组比对照组分别低15.59%和24.53%。保育猪46日龄~60日龄之间,阳性 PCV-2抗体 S/P 均值试验组比对照组分别低15.42%、19.66%和12.70%。保育猪转栏时,试验组比对照组平均末重高12.74%(P <0.01),平均日增重提高16.90%(P <0.01),成活率高1.67%。免疫组化结果显示,相对于空白组,添加组空肠和小肠组织中的 PRRSV 抗原的阳性表达几乎为0。试验结果为特异性抗体用于PRRSV 和 PCV-2的防控提供了参考。

著录项

相似文献

  • 中文文献
  • 外文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号