Objective To observe the relationship between red blood cell distribution width (RDW) and APACHEⅡ in critically ill patients .Methods In 398 critically ill patients ,APACHEⅡand RDW were recorded . According to APACHEⅡscore ,all patients were divided into A group(≤10) ,B group(11-20) ,C group (21-30) and D group(>30) ,then we compared the level of RDW .RDW was compared between survival group and death group .Then we analyzed the relationship between RDW and APACHEⅡ .Results In B group ,RDW were high-er than those in A group ,but the difference was not significant (P>0.05) .RDW in C group were higher than those in B group (P<0.01) .RDW in D group were higher compared with C group (P<0.01) .In death group , APACHEⅡ score was higher than that in survival group (P<0.01) ,RDW were higher (P<0.01) .APACHEⅡ score correlated well with the mean level of RDW (P<0.01) .Conclusion RDW is the good factor in evalua-tion of condition and prognosis in the critically ill patients .%目的研究危重病患者红细胞分布宽度与急性生理和慢性健康状况评分(APACHE)Ⅱ的相关性,探讨方便、有效的预测危重病病情、判断预后,且具有临床实用价值的监测指标.方法记录398例患者入院后APACHEⅡ评分及红细胞分布宽度,比较不同APACHEⅡ评分组入院时红细胞分布宽度水平是否存在差异;比较存活组与死亡组患者的APACHEⅡ评分与红细胞分布宽度水平;评估红细胞分布宽度与APACHEⅡ评分之间的相关性.结果APACHEⅡ评分11~20分(B组)与≤10分(A组)比较,红细胞分布宽度有升高趋势,但差异无统计学意义(P>0.05),APACHEⅡ评分21~30分(C组)高于B组,APACHEⅡ评分>30分(D组)亦高于C组,差异有统计学意义(P<0.01);死亡组患者APACHEⅡ评分高于存活组,入院时红细胞分布宽度水平高于存活组,差异有统计学意义(P<0.01);入院时红细胞分布宽度水平与APACHEⅡ评分呈正相关(r=0.602,P<0.01).结论随着患者病情的加重,APACHEⅡ评分增加,红细胞分布宽度水平增加;入院时红细胞分布宽度水平与危重病程度正相关,是反映危重患者病情严重程度和预测患者转归较好的指标.
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