This paper uses questionnaire survey to study the mental health of 2988 college students. It is found the number of people with psychological distress is 693, account for 23.19% of the total number of participants. And the number of people with depression symptoms is 347, account for 11.61% of the total number of participants. 30 students in the students who have depression are randomly selected for semi-structured interviews. It is found that there psychological characteristics are: personal subjective pain, physical symptoms, effect on life and learning, others do not understand and so on. 144 students with depression symptoms in the experimental group are intervened by Integration Therapy of Five Wefts for 1 year. That effectively alleviates the depression of students in the experimental group.%本研究采用问卷调查法对2988名大学生进行心理健康状况研究，发现有心理困扰的人员693人，占参加测验人员总数的23.19%。有抑郁症状的人数为347人，占总测查人数的11.61%。从有抑郁倾向的同学中随机抽取了30人进行半结构式访谈，发现其心理特点有：个人主观痛苦、躯体症状明显、影响生活与学习、他人不理解等。实验组144名抑郁症状明显的被试进行1年的“五纬统一整合疗法”干预，有效减轻了实验组大学生的抑郁症状。
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