This paper presents six influencing factors of technological innovation performance in vocational college by taking technical innovation performance as the research object, based on the theory of regional innovation system and the present situation of their technical innovation. By using factor analysis, three key influencing factors are obtaining such as technical innovation resources, technical innovation risk, and technical innovation environment. It also analyzes the relationships and the degree of influence between the three key influencing factors and technical innovation performance in vocational college by principal component regression analysis. The final analysis conclusion is that technical innovation resources have the greatest impact on technical innovation performance in vocational college.%以高职院校科技创新绩效为研究对象，基于高职院校科技创新的现状和区域创新系统理论，提出科技人才、科技经费、研发过程、创新政策、产业发展、应用转化等六个方面的影响因素假设，通过主成分分析得出科技创新资源、科技创新过程和科技创新环境三个关键影响因素。通过实证研究，得出三个关键影响因素均对科技创新绩效具有显著正向作用，通过建立高职院校科技创新绩效的线性回归方程，有效确定了各个影响因素的影响程度，得出科技创新资源因素对高职院校科技创新绩效影响作用最大的结论。
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