Objective To compare the penetration abilities of resin infiltration into natural initial caries lesions with those of adhesive in vitro. Methods Thirty-six extracted human molars and premolars showing proximal white spot lesions were selected. Teeth roots were removed, and the crowns were cut across the caries lesions perpendicular to the surface. Corresponding lesion halves were etched for 2 min with 15% hydrochloric acid gel and were subse-quently treated with either adhesive or resin infiltration. Specimens were observed with confocal laser scanning mi-croscopy (CLSM) in dual fluorescence mode. In confocal microscopic images, penetration depth (PD) and lesion depth (LD) were defined as the distance from the surface to the deepest point of red and green fluorescence, respectively. The penetration percentages (PP) were calculated. Results At the same level of caries, mean maximum lesion LD were comparable for both lesion halves (P>0.05). But mean maximum PD and PP of the resin infiltration were significantly higher than those of the adhesive (P<0.01). Conclusion Penetration of enamel caries lesions is observed in the ad-hesive and the resin infiltration. But the resin infiltration is capable of penetrating almost completely into enamel parts of natural caries lesions.%目的 比较渗透树脂和粘接剂在自然形成的早期龋损中的渗透能力.方法 选取36颗邻面有白垩色早期龋损的离体恒磨牙和前磨牙,垂直于龋损表面将牙齿一切为二.两半病损用15％的盐酸酸蚀2min,随后一半病损用渗透树脂处理,另一半病损用粘接剂处理.用激光扫描共聚焦显微镜(CLSM)在双荧光模式下进行观察,测量树脂的渗透深度(PD)和病损深度(LD),并且计算渗透百分数(PP).结果 在相同的病损组织学分级中渗透树脂组和粘接剂组间LD的差异无统计学意义(P＞0.05),但是两组PD和PP间差异有统计学意义(P＜0.01),渗透树脂组明显高于粘接剂组.结论 粘接剂和渗透树脂对早期龋损均有渗透作用,但是渗透树脂渗透更深,甚至能完全地渗入到病损内.
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