Objective:To illustrate the change tendency of female sex hormones during the menstrual cycle of healthy women with different personality traits.Methods:Eighty healthy women with regular menstrual cycle were recruited and evaluated by Revised Eysenck Personality Questionnaire-Short Scale for Chinese (EPQ-RSC).According to the score of different aspects in EPQ-RSC, such as Neuroticism (N),Psychoticism (P)and Extraversion (E),the subjects were divided into high group and low group.Then blood were taken from both groups during the period (day 2 to 4),the late follicular phase (day 1 1 -1 3)and the late luteal phase (day 22-24)for three consecutive menstrual cycles.Estrogen (E2),follicle stimulating hormone (FSH),luteinizing hormone (LH),progesterone (Prog),testosterone (T)and prolactin (PRL)were tested.Results:On the Neuroticism there was no signifi-cant difference between the two groups (P >0.05).However,on the Psychoticism the high-P-group showed significant increasing of the FSH in the period,late follicular phase,late luteal phase and the LH in the period and late follicular phase comparing with the low-P-group (P <0.05).There was also significant difference in the reduction of T in M3 period.On the Extraversion,the high-E-group showed significant increase of the E2 in M2 period,the Prog in M3 period,and the FSH in M1 period than the low-E-group (P <0.05).But in M3 the LH of low-E-group was clearly significantly higher than that of high-E-group.The T in M2 /M3 period of the low-E-group also obviously significant higher than the high-E-group.Conclusion:Different personality characteristics may af-fect the change of the sex hormones of healthy women.%目的：探讨不同人格特质的健康女性月经周期性激素的变化趋势。方法：选取月经周期规律的健康女性并按照EPQ －RSC 量表的三个维度即 N（神经质）、P（精神质）、E（内外向）进行分组，连续三个月经周期分别于受试者的月经期、卵泡晚期、黄体中晚期抽取空腹血检测性激素。结果：各激素水平在月经期处于相对稳定低水平，在卵泡晚期波动最大，在黄体中晚期变化急剧；EPQ －RSC 量表的三个维度对健康女性月经周期性激素变化趋势存在一定的影响。结论：各激素在三个检测时相内的变化趋势符合现代医学对性激素随月经周期变化趋势的阐述；心境状态对性激素变化存在一定的影响。外向型性格、低精神质状态使女性激素水平变化趋势更符合生理态。
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