首页> 中文期刊> 《世界胃肠病学杂志:英文版》 >Methotrexate induced sprue-like syndrome

Methotrexate induced sprue-like syndrome

         

摘要

A 52 year-old male patient diagnosed of ankylosing spon-dylitis presented with an iron deficiency anemia after a ten-month treatment of methotrexate. He did not respond to treatment with oral iron not a proton pump inhibitor and an upper endoscopy was performed. The histological study of the duodenal biopsies showed villus atrophy. After removing the methotrexate, administrating intra-muscular iron and undertaking a gluten-free diet, the histological and analytical alterations progressively resolved.

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