cqvip:The diagnostic yield of capsule endoscopy depends on the quality of visualization of the small-bowel wall and complete passage through the small bowel. This study examined the effect of bowel preparation on the volume of intestinal content and on small-bowel transit. Sixty-one consecutive patients (34 men, 27 women; mean age 56 years, range 17-88 years)were enrolled in the study. Although not randomized, 33 patients received a bowel preparation, and 28 had no preparation. Gastric emptying, small-bowel transit time, overall preparation assessment, and bowel-wall visualization were evaluated by 3 investigators who were unaware of whether the patient had undergone bowel preparation. Small-bowel transit time was significantly shorter in patients with bowel preparation (median 213 minutes: 95%CI[190, 267]) than in those without preparation (median 253 minutes: 95%CI[228, 307]) (p < 0.01). The capsule reached the cecum in 97%of patients in the bowel-preparation group, compared with 76%in the nonpreparation group (p = 0.02). Bowel preparation improved the quality of visualization significantly; this effect was more pronounced in the distal small bowel. This study demonstrated that bowel preparation accelerates small-bowel capsule transit and leads to a higher rate of complete capsule endoscopy. Visualization of the small bowel was improved by bowel preparation. Bowel preparation before capsule endoscopy is recommended.
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