cqvip:Background. Lichen nitidus is a rare condition, which may be a cause of palmop lantar hyperkeratosis. We report two cases. Case reports. A 53 year-old woman p resented with a dry and fissured palmoplantar hyperkeratosis. Histological exami nation of a biopsy showed the typical features of lichen nitidus. Significant im provement was obtained with acitretin. A few months later, multiple lichen nitid us papules appeared on the limbs and the abdomen. A 67 year-old woman was refer red to us for a fissured, disabling palmoplantar hyperkeratosis refractory to to pical steroids. Histological examination led to the diagnosis of lichen nitidus. Local PUVAtherapy resulted in the cleaning of her lesions. Later, typical papul es of lichen nitidus appeared on her elbows. Discussion. Nineteen cases of palmoplantar localization of lich en nitidus have been described. The features are usually tiny yellow papules ’b ut sometimes a nonspecific keratoderma resembling chronic eczema. Palmoplantar i nvolvement of lichen nitidus maybe isolated or associated with cutaneous lesions on unusual sites. Oral retinoids and local PUVA are effective treatments.
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