Objective To investigate the clinical efficacy of platelet-rich plasma(PRP) injection in treatment of frozen shoulder. Methods 60 cases of frozen shoulder patients from January 2014 to July 2015 were included in this study,which were randomly divided into observation and control groups,30 cases each. Observation group was given autologous PRP injections in pain point,and control group was given 1% procaine plus hydrocortisone acetate.All patients were injected 2 weeks,for 3 times in a course of treatment. Using UCLA shoulder score(the University of California) and visual analogue scale VAS pain score (0 -10 points),the score of the 2 groups were compared before treatment,and 1 week,1 month,3 months,6 months after treatment of shoulder pain. Results All patients were followed up for 6 months. Before treatment,the difference of UCLA shoulder score,visual analogue scale VAS pain score between the observation group and the control group was not statistically significant (P>0.05). Compared with the scores before treatment,the differences of UCLA shoulder score and visual analogue scale VAS pain score in each observation point after treatment were statistically significant (P<0.01). The UCLA shoulder score and visual analogue scale VAS pain scores in observation group were lower than that in the control group in 1 week after treatment(P<0.05),but the differences of UCLA shoulder score and visual analogue scale VAS pain scores between observation group and control group were not statistically significant in 1 month after treatment(P>0.05). Furthermore,the UCLA shoulder score and visual analogue scale VAS pain scores in observation group were better than that in the control group in 3 month and 6month after treatment(P<0.05). Conclusion The PRP injection therapy in frozen shoulder is safe and effective. It can promote tendon repair,elimination of the rotator cuff and joint capsule adhesions in order to cure frozen shoulder.%目的 探讨富血小板血浆痛点注射治疗肩周炎的临床疗效.方法 2014年1月至2015年7月,将60例肩周炎患者随机分为观察组和对照组,每组各30例.观察组进行自体富血小板血浆(PRP)痛点注射治疗,对照组进行1%普鲁卡因加醋酸氢化可的松局部注射治疗,两组患者均注射1次/2周,3次为1个疗程.采用美国加州大学肩关节评分(UCLA)标准、视觉模拟评分法(VAS)疼痛评分标准(0~10分),比较两组在治疗前,治疗后1周、1个月、3个月、6个月的肩关节疼痛、功能评分.结果 所有患者均获得6个月随访.治疗前的观察组与对照组的UCLA评分、VAS疼痛评分接近,差异无统计学意义(P>0.05).两组治疗后各观察点的UCLA评分、VAS疼痛评分与治疗前比较,差异均有统计学意义(P<0.01).在治疗后1周时观察组的UCLA评分、VAS疼痛评分差于对照组,差异有统计学意义(P<0.05);治疗1个月时观察组与对照组的两项观察指标差异无统计学意义(P>0.05);而治疗3个月、6个月时观察组的UCLA评分、VAS评分优于对照组,差异有统计学意义(P<0.05).结论 富血小板血浆痛点注射治疗肩周炎是安全、有效的.该疗法能够促进肌腱的修复、消除肩袖、关节囊的粘连效果,从而能治愈肩周炎.
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