目的 观察对比重组人表皮生长因子(rhEGF)与红外线照射促进伤口愈合的临床疗效.方法 286例皮肤创伤经清创术后随机分为两组,A组每日使用rhEGF治疗,B组每日进行红外线照射治疗,观察创面愈合时间、创面愈合质量、瘢痕增生情况.结果 A组创面愈合时间(6.76±1.83)d较B组(7.52±1.61)d缩短,A组愈合良好率88.1%高于B组的72.7%,A组瘢痕组织增生发生率2.1%低于B组的7.7%,差异具有统计学意义(P<0.05).结论 rhEGF治疗与红外照射治疗相比能缩短皮肤创伤的愈合时间,提高创面愈合质量,减少瘢痕增生,有重要临床应用价值.%Objective To observe and compare the clinical effect of recombinant human epidermal growth factor (rhEGF) and infrared irradiation on wound healing. Method 286 cases of skin wound after debridement were randomly divided into two groups:group A were daily given recombinant human epidermal growth factor (rhEGF) treatment,while group B received daily infrared irradiation treatment,observed the time of wound healing,the quality of wound healing and scar hyperplasia. Results The wound healing time in group A was shorter than that in group B, the quality of wound healing was improved,the incidence of scar hyperplasia was decreased,and significantly statistical differences could be found (P<0.05). Conclusions Study results indicate that recombinant human epidermal growth factor(rhEGF) treatment can shorten the healing time of skin trauma,improve the quality of wound healing and reduce scar hyperplasia. So it absolutely has important clinical application value.
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