目的 观察甲状腺全切术对于患者血清甲状旁腺素(PTH)等相关指标的影响.方法 2015年1月至2016年12月间采取甲状腺全切术治疗的104例患者作为观察对象,根据手术范围将全部患者划分为单纯组与联合组,单纯组患者手术切除范围为单纯甲状腺切除,联合组为甲状腺全切联合颈淋巴结清扫术.多点监测两组患者PTH及血清钙水平,检测两组患者术前及术后3d时的三碘甲状腺原氨酸(T3)、甲状腺素(T4)、促甲状腺激素(TSH)水平并进行比较术后5d统计两组低钙血症及甲状旁腺功能减退发生率,分析其与PTH水平的相关性.结果 单纯组患者PTH从术前至术后5d多点监测整体优于联合组(P<0.01);单纯组患者血钙水平从术前至术后5d多点监测整体优于联合组(P<0.05).治疗前两组T3、T4、TSH差异均无统计学意义(P>0.05);治疗后两组T3、T4均明显下降、TSH均明显上升,组内比较差异有统计学意义(P<0.01);治疗后单纯组T3低于联合组(P<0.05),T4、TSH组间比较差异无统计学意义(P>0.05).单纯组低钙血症发生率为42.22%、甲状旁腺功能减退发生率为46.67%,联合组低钙血症发生率为62.71%、甲状旁腺功能减退发生率为66.10%;单纯组均低于联合组(P<0.05).低钙血症发生与PTH水平间具有高度正相关性(0.80.05). After treatment, two groups of T3 and T4 were decreased, TSH were significantly increased in group, the difference was statistically significant,T3 was lower than that of pure in the combination group (P<0.05),T4 and TSH was not statistically significant between the two groups(P>0.05). Simple group of hypocalcemia incidence was 42.22%, hypothyroidism incidence rate was 46.67%,the incidence rate was 62.71% in combined group of hypocalcemia and hypoparathyroidism occurred in 66.10%. The simple group was lower than the combined group(P<0.05). With a high degree of positive correlation between incidence of hypocalcemia with PTH levels of 0.8展开▼
