Objective Laparoscopic gastric cancer radical gastrectomy treatment early gastric cancer patients to the influence of the postoperative recovery. Methods Early gastric cancer patients with D2 radical gastrectomy were divided into two groups:the laparoscopic group and open surgery group. Two groups take the same preoperative preparation,extracting patients peripheral venous blood to test blood insulin concentration before surgery and after surgical abdomen closed,blood glucose concentration,and the steady state model evaluation method(HOMA)calculation of insulin resistance index,insulin sensitive index,and at the same time,for the first time to patients postoperative exhaust time,postoperative pain assessment,the postoperative complications,and the length of hospital stay were observed. Results from September 2010 to March 2012, laparoscopic gastric cancer radical gastrectomy group included in 26 patients and open group included in 28 patients. The laparoscopic group operation time significantly longer than open group(P<0.05);Two groups of patients with preoperative blood glucose,insulin concentration,IR,insulin sensitive index there are no significant statistical difference,Postoperative cavity mirror group blood sugar concentration,blood insulin concentrations and IR index are lower than laparotomy group(P<0.05),and insulin sensitive index is higher than laparotomy group(P<0.05);there were no significant differences about postoperative complications and postoperative pain assessment,postoperative hospital stay(P>0.05).Conclusion After laparoscopic gastric cancer radical gastrectomy,it can effectively ameliorate the insulin resistance degree,reduce patients blood sugar level,But the recovery of patients did not improve.%目的：探讨腹腔镜胃癌根治术治疗早期胃癌对患者术后恢复的影响。方法将拟实施胃癌D2根治术的早期胃癌患者分为经腹腔镜胃癌根治术组与开腹胃癌根治术组。两组采取相同的术前准备，并于手术前和手术关腹后抽取患者外周静脉血检测血胰岛素浓度、血糖浓度，并利用稳态模式评估法（HOMA）计算胰岛素抵抗指数、胰岛素敏感指数，同时对患者术后首次排气时间，术后疼痛评估、术后并发症、术后住院时间进行观察。结果自2010年9月至2012年3月间，腹腔镜胃癌根治术组纳入26例患者，开腹胃癌根治术组纳入28例患者，经腹腔镜组手术时间长于开腹组手术时间（P<0.05）；术前两组患者的血糖、胰岛素浓度、胰岛素抵抗（IR）指数、胰岛素敏感指数差异均无统计学意义；术后腹腔镜组血糖浓度、血胰岛素浓度和IR指数均低于开腹组（P<0.05），而胰岛素敏感指数高于开腹组（P<0.05）；两组患者术后并发症、术后疼痛评估、术后住院时间均未见明显差异（P>0.05）。结论对于早期胃癌患者实施经腹腔镜胃癌根治术，可有效地改善术后胰岛素抵抗程度，但患者的康复速度并未得到改善。
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