ObjectiveTo analyze the correlation between central aortic pressure and brachial artery pressure and the impact with aged and blood pressure elevation in elderly.MethodsTwo hundred and five old patients who were hospitalization in our department from March,2013 to January,2014 were enrolled this study. The central aortic pressure of each patient was measured by Sphygmo Cor(Australia),respectively,and compared with brachial artery pressure.ResultsCompared with central aortic pressure,the brachial artery systolic pressure and pulse pressure rose in both hypertension group and non-hypertension group(P<0.01).Compared with the subjects with year less than 70 years,the brachial artery diastolic pressure and the central aortic diastolic pressure were lowered in subjects with year more than 70 years(P<0.01,orP<0.05),pulse pressure of both central aortic pressure and brachial artery pressure,augmentation pressure and augmentation index of central aortic were significantly increased (P<0.01).Compared with hypertension patients of grade-Ⅰ,systolic pressure and pulse pressure of brachial artery,augmentation pressure and augmentation index of central aortic were significantly higher in hypertension patients of grade-Ⅲ(P<0.05).ConclusionThere is significant difference between central aortic pressure and brachial artery pressure in elderly. The elasticity of artery blood vessel is decline,stiffness is raised along with aged and blood pressure elevation,and the result is the degree of atherosclerosis aggravation.%目的：对老年人的中心动脉血压（CAP）和肱动脉血压进行相关分析，探讨老年人CAP与肱动脉压的关系以及年龄、血压升高对其的影响。方法选取2013年3月至2014年1月老年患者205例（高血压患者152例，非高血压患者53例），采用动脉脉搏波分析仪测量CAP，依据年龄和高血压分级分组，比较CAP与肱动脉血压的差异变化。结果与中心动脉压比较，无论是高血压组还是非高血压组，肱动脉收缩压（SBP）、脉压（PP）显著增高（P<0.01），舒张压（DBP）下降。与<70岁年龄组比较，>70岁人群的DBP、中心动脉舒张压（cDBP）下降（P<0.01，或P<0.05），PP和中心动脉脉压（cPP）增大（P<0.01），中心动脉增强压（AP）和增强指数（AIx）显著增高（P<0.01）。与Ⅰ级高血压患者比较，Ⅲ级高血压患者的SBP、PP、AP和AIx明显增高，差异均有统计学意义（P<0.05）；Ⅰ级高血压患者与Ⅱ级高血压患者比较，以及Ⅱ级高血压患者与Ⅲ级高血压患者比较，SBP、PP、AP和AIx呈逐渐增高趋势，但差异无统计学意义（P>0.05）。结论无论是高血压患者还是非高血压人群，肱动脉血压与CAP有显著差异；随着增龄与血压的升高，外周动脉血管弹性下降，僵硬度上升，动脉粥样硬化程度加重。
展开▼
