目的 探讨加压和深蹲活动时生物型股骨假体周围组织液的力学性能.方法 应用Mimics建模软件构建包括肉芽组织、松质骨和组织液在内的股骨近端和髋关节假体有限元模型,模拟加压和深蹲两种活动姿态,分析组织液在不同活动时的流动性能.结果 研究证实加压活动时,组织液出现低速流动,主要分布区域位于假体后内侧肉芽组织和假体远端松质骨区域.深蹲活动时组织液流动速度较快,主要分布于假体后内侧肉芽组织内和假体周围广泛松质骨区域.结论 组织液在深蹲活动时在假体周围广泛流动且速度较快,不利于假体周围骨痂生成且易造成骨质吸收,是造成全髋关节术后假体松动的可能因素.%Objective To explore the biomechanical effect of micromotion-induced fluid around biological prosthesis in different posture with finite element analysis. Methods Finite element model including cortical bone,trabecular bone,granulation tissue,fluid and prosthesis were established with Mimics software. Fluid condition was evaluated in compression and deep knee bend. Results In compression action,tissue fluid flow at a low speed,the main distribution area was located in the medial granulation tissue and distal cancellous bone area around the implant prosthesis. Under the deep knee bend motion,the flow rate of the tissue fluid was relatively fast,mainly distributed in the medial granulation tissue and the wide cancellous bone area around the prosthesis. Conclusions In deep knee bend posture,the tissue fluid flow is fast and widely around the prosthesis,is not conducive to callus formation and likely to cause bone absorption around prosthesis,which is a possible factor of prosthesis failure in early stage of total hip arthroplasty.
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