目的：分析经皮冠状动脉介入（PCI ）治疗围手术期规范应用抗生素的成效。方法：回顾性调查2011年1月－12月心血管内科择期行PCI手术患者212例作为未规范组，2012年1月－12月心血管内科对择期行PCI手术规范围手术期抗生素应用的228例作为规范组，对患者术后平均住院日、住院药物费用、抗生素使用情况、术后发热情况进行分析。结果：规范围手术期抗生素应用后，抗生素不合理使用率从97.17％下降至0％；术后住院日由5.21±2.18天下降至3.71±1.49天（ P＜0.05）；住院药物费用从6421.1±2619.6元下降至5857.3±2493.8元（ P＜0.05）；术后发热2组差异无统计学意义（ P＞0.05）。结论：依据卫生部相关规定规范PCI围术期抗生素应用，能缩短住院周期，减轻患者经济负担，不会增加术后发热发生率。%Objective] To find out and evaluate perioperative prophylactic application of antibiotics in patients undergoing coro-nary intervention surgery in our hospital pre and post specification .[Method] A retrospective survey was carried out .211 pa-tients undergoing coronary intervention during Jan 2011 to Dec 2011 were included in pre-specification group and 228 patients undergoing coronary intervention during Jan 2012 to Dec 2012 were included in post-specification group .The average length of stay ,drug cost ,the fever post operation and the application of antibiotics were evaluated .[Result] The perioperative prophy-lactic antibiotics application rate reduced from 100% to 0% after specification .The average length of stay post-operation re-duced to 3.71 ± 1.49 from 5.21 ± 2.18 pre-specification ( P=0.015 ) and the drug cost during hospital drop to 5857.3 ± 2493.8 yuan from 6421.1 ± 2619.6 yuan pre-specification ( P=0.032 ) .The fever post-operation between the two groups was not statistically significant .[Conclution] It is necessary to standard the Antibiotics in Patients Undergoing Coronary Inter-vention according to< implement of the Guiding Principles of Clinical Use of Antibiotics > to shorten the length of stay ,light the burden of the patients .Furthermore ,it will not increase incidence of fever post-operation .
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