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Evaluation of antitumor property of extracts and steroidal alkaloids from the cultivated Bulbus Fritillariae ussuriensis and preliminary investigation of its mechanism of action

机译：栽培的贝母贝母提取物和甾体生物碱的抗肿瘤性质评价及其作用机理的初步研究

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BackgroundCancer is well known as a leading cause of death in the world. At present, it is the very active area to search for anticancer drugs from natural products. In this study, we evaluated the antitumor property of chloroform extract (CE), n-hexane extract (HE), water extract (WE) and steroidal alkaloids from the cultivated Bulbus Fritillariae ussuriensis (BFU) and its preliminary mechanism for its action was investigated.

机译：背景癌众所周知是世界上主要的死亡原因。目前，从天然产物中寻找抗癌药物是非常活跃的领域。在这项研究中，我们评估了氯仿提取物（CE），正己烷提取物（HE），水提取物（WE）和栽培的乌苏贝母（BFU）的甾体生物碱的抗肿瘤特性，并研究了其作用的初步机理。。

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期刊名称 BMC Complementary and Alternative Medicine
作者
Dongdong Wang; Yun Jiang; Ke Wu; Shu Wang; Yitao Wang;
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作者单位

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年(卷),期 2015(15),-1
年度 2015
页码 29
总页数 11
原文格式 PDF
正文语种
中图分类
关键词
Bulbus Fritillariae ussuriensis Alkaloids Antitumor Cell cycle Microvessel density Caspase-3;

机译：贝母贝母;生物碱;抗肿瘤;细胞周期;微血管密度;Caspase-3;

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专利

1. Evaluation of antitumor property of extracts and steroidal alkaloids from the cultivated Bulbus Fritillariae ussuriensis and preliminary investigation of its mechanism of action [J] . Dongdong Wang, Yun Jiang, Ke Wu, BMC Complementary and Alternative Medicine . 2015,第1期

机译：栽培的贝母贝母提取物和甾体生物碱的抗肿瘤性质评价及其作用机理的初步研究
2. In vitro and in vivo antitumor activity of bulbus fritillariae cirrhosae and preliminary investigation of its mechanism [J] . WangD.-D., FengY., LiZ., Nutrition and Cancer: An International Journal . 2014,第1a4期

机译：川贝母的体外和体内抗肿瘤活性及其作用机理的初步研究
3. Global detection and semi-quantification of Fritillaria alkaloids in Fritillariae Ussuriensis Bulbus by a non-targeted multiple reaction monitoring approach [J] . Wang Li, Yao Zhong Ping, Li Ping, Journal of separation science. . 2016,第2期

机译：非目标多反应监测方法对乌苏贝母中贝母生物碱的整体检测和半定量
4. SUPERCRITICAL EXTRACTION OF INDOLE ALKALOIDS FROM Tabernaemontana catharinensis: AN EVALUATION OF THE COSOLVENT ON THE EXTRACT COMPOSITIONS [C] . Camila G. Pereira, Marcia O.M. Marques, Antonio C. Siani, International Symposium on Supercritical Fluids Tome 1: Natural Products, Process amp; Equipment Development; 20030428-20030430; Versailles; FR . 2003

机译：超临界萃取中华Tab吲哚碱的研究-提取物组成上溶剂的评价。
5. Design and biological evaluation of novel antitumor agents with mechanisms of action against topoisomerase II and/or G-quadruplexes. [D] . Kim, Mu-Yong. 2002

机译：具有抗拓扑异构酶II和/或G-四链体作用机制的新型抗肿瘤药的设计和生物学评估。
6. Optimization of Extraction and Enrichment of Steroidal Alkaloids from Bulbs of Cultivated Fritillaria cirrhosa [O] . Dongdong Wang, Shu Wang, Qingdan Du, -1

机译：栽培贝母鳞茎中甾体生物碱的提取富集工艺优化
7. Evaluation of antitumor property of extracts and steroidal alkaloids from the cultivated Bulbus and preliminary investigation of its mechanism of action [O] . 2015

机译：培养的牛ul提取物和甾体生物碱的抗肿瘤性能评估及其作用机理的初步研究

Evaluation of antitumor property of extracts and steroidal alkaloids from the cultivated Bulbus Fritillariae ussuriensis and preliminary investigation of its mechanism of action

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