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首页> 美国卫生研究院文献>British Journal of Preventive Social Medicine >Hazardous chemicals: psychological dimensions of the health sequelae of a community exposure in Texas.
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Hazardous chemicals: psychological dimensions of the health sequelae of a community exposure in Texas.

机译：有害化学物质：德克萨斯州社区暴露后遗症的心理影响。

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STUDY OBJECTIVE--A chemical spill from an oil refinery exposed the local community to more than 40,000 lb of highly toxic and corrosive hydrofluoric acid. A community based symptom prevalence study found an association between exposure and physical symptoms: the psychological impact of the disaster and its potential effect on the reporting of physical symptoms is examined here. DESIGN--The study used a population based survey design consisting of two phases: phase I, the exposure phase, and, phase II, the symptom prevalence phase. SUBJECTS--In phase I, information indicative of exposure was collected on 10,811 individuals in a door to door survey of a geographically defined area. In phase II, symptom prevalence information was gathered through in-person interviews with 2509 subjects selected from the phase I census in a sampling scheme that balanced across the exposure categories with regard to age, gender, and predisposition. The refusal rate in both phases was < 5%. MEASUREMENT AND MAIN RESULTS--Stepwise logistic regression analyses were used to assess the relative predictive importance of psychological variables and hydrofluoric acid exposure in explaining the reported physical symptoms two years after the disaster. The findings show a linear relationship between the level of hydrofluoric acid exposure and the degree of psychological stress two years after the accident. High exposure had a long term (more than two years) impact on physical health for some self reported symptoms, even after controlling for the psychological impact. Some physical symptom reports, however, were better explained by psychological status than by exposure to hydrofluoric acid. The physical symptoms for which exposure was the major predictor were those for which the biological plausibility of a relationship with hydrofluoric acid exposure was direct. CONCLUSIONS--Measures of psychological status should be included in symptom studies of health sequelae to man-made disasters so that the physical effects of exposure can be more accurately assessed.
机译：研究目的-来自一家炼油厂的化学泄漏使当地社区暴露于40,000磅以上的剧毒和腐蚀性氢氟酸中。一项基于社区的症状患病率研究发现，暴露与身体症状之间存在关联：此处考察了灾难的心理影响及其对身体症状报告的潜在影响。设计-该研究使用了基于人群的调查设计，包括两个阶段：第一阶段（暴露阶段）和第二阶段（症状流行阶段）。主题-在第I阶段，在对地理区域的门到门调查中，收集了10,811个人的暴露信息。在第二阶段中，通过对从第一阶段人口普查中选出的2509名受试者进行面对面访谈，收集了症状发生率信息，该抽样方案在年龄，性别和易感性的各个暴露类别之间保持平衡。两个阶段的拒绝率均<5％。测量和主要结果-逐步Logistic回归分析用于评估心理变量和氢氟酸暴露在解释灾难两年后报告的身体症状方面的相对预测重要性。调查结果表明，事故发生两年后，氢氟酸暴露水平与心理压力程度之间存在线性关系。即使在控制了心理影响之后，高暴露量也会对某些自我报告的症状造成长期（超过两年）的身体健康影响。但是，通过心理状态比通过暴露于氢氟酸可以更好地解释某些身体症状的报告。暴露为主要预测指标的物理症状是与氢氟酸暴露相关的生物学合理性直接相关的物理症状。结论-在人为灾难的健康后遗症的症状研究中应包括心理状态的衡量指标，以便可以更准确地评估暴露的物理影响。

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