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Observations on syphilis in Addis Ababa. 2. Prevalence and natural history.

机译:亚的斯亚贝巴的梅毒观察。 2.患病率和自然历史。

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摘要

Sera from various groups were tested for syphilis by cardiolipin, fluorescent treponemal antibody-absorbed (FTA-ABS), and treponemal haemagglutination (TPHA) tests. The proportion of positive results, 12.7%, obtained from an unselected urban population suggested that the prevalence of the disease had declined since 1953. The probable explanation is the widespread use of penicillin. Late manifestations of syphilis are much rarer in Ethiopia than would be predicted from the high incidence at the infectious stage and, if present, they affect the cardiovascular system. These findings confirm old observations. Llymphocytes from Ethiopians with early syphilis did not proliferate when cultured with Treponema pallidum in vitro, in contrast with cells from patients with cardiovascular syphilis. These findings differed from observations made previously on patients in England with early syphilis.
机译:通过心磷脂,荧光性肾小球体抗体吸收(FTA-ABS)和肾小球性血球凝集(TPHA)测试来测试梅毒。从未选定的城市人口中获得阳性结果的比例为12.7%,表明该疾病的流行率自1953年以来有所下降。可能的解释是青霉素的广泛使用。在埃塞俄比亚,梅毒的晚期表现比在感染期高发所预测的要少得多,而且如果存在的话,它们会影响心血管系统。这些发现证实了以前的观察。与患有梅毒螺旋体的患者的细胞相比,埃塞俄比亚早期梅毒的淋巴细胞在体外与苍白螺旋体一起培养时不会增殖。这些发现与先前对英格兰早期梅毒患者的观察结果不同。

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