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Seroepidemiology of chlamydia in Costa Rica.

机译:哥斯达黎加衣原体的血清流行病学。

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摘要

A population-based study of the sero-epidemiology of chlamydia was performed among a nationally representative sample of 760 Costa Rican women aged 25 to 59 years. Interviews and sera collection were completed between September 1984 and February 1985. The overall seroprevalence of chlamydial antibodies among these women was 56.1%. Women 25 to 39 years of age had a seroprevalence of 51.1%, while women 40 to 59 years of age had a seroprevalence of 64.2%. Women who reported no prior sexual activity had a seroprevalence rate of 48.6%, compared with a seroprevalence rate of 80.7% among women who reported three or more lifetime sexual partners. The geometric mean titre (GMT) of seropositive women ranged from 34.4 among the women who reported no prior sexual activity to 155.0 among the women with three or more lifetime sexual partners. Sero-positivity was more consistently associated with sexual activity than with age. Women with serological evidence of past Herpes simplex virus type 2 (HSV-2) or syphilis infection were more likely to be seropositive than were women without evidence of exposure to these sexually transmitted diseases, even when controlled for age and the number of lifetime sexual partners. The seropositivity among never sexually active women indicates the probable presence of Chlamydia pneumoniae infections, while the high seroprevalence of chlamydial antibodies among the sexually active women suggests that sexually transmitted Chlamydia trachomatis infections represent a public health problem not previously quantified in Costa Rica. Further seroepidemiological and/or culture studies are warranted to determine the incidence and prevalence of sexually transmitted chlamydial infection among men and younger women.
机译:对760名年龄在25至59岁的哥斯达黎加妇女进行了全国代表性的抽样调查,对衣原体的血清流行病学进行了一项基于人群的研究。在1984年9月至1985年2月之间完成了访谈和血清收集。这些妇女中衣原体抗体的总体血清阳性率为56.1%。 25至39岁的女性血清阳性率为51.1%,而40至59岁的女性血清阳性率为64.2%。以前没有进行过性活动的妇女的血清阳性率是48.6%,而报告过三个或更多毕生性伴侣的女性的血清阳性率是80.7%。血清反应阳性妇女的几何平均滴度(GMT)范围是从没有报告过性行为的妇女中的34.4到有三个或更多终生性伴侣的妇女中的155.0。血清阳性与性活动比与年龄更一致。血清学证据表明既往有单纯疱疹病毒2型(HSV-2)或梅毒感染的女性比没有暴露于性传播疾病证据的女性更倾向于血清反应阳性,即使在控制了年龄和终生性伴侣的情况下也是如此。从未从事过性活动的妇女中的血清阳性表明可能存在肺炎衣原体感染,而从事性活动的妇女中衣原体抗体的血清阳性率高表明性传播的沙眼衣原体感染代表了以前在哥斯达黎加无法量化的公共卫生问题。有必要进一步进行血清流行病学和/或文化研究,以确定男性和年轻女性中性传播的衣原体感染的发生率和患病率。

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