首页> 美国卫生研究院文献>Clinical and Diagnostic Laboratory Immunology >Note: Prevalence of CagA and VacA Antibodies in Children with Helicobacter pylori-Associated Peptic Ulcer Compared to Prevalence in Pediatric Patients with Active or Nonactive Chronic Gastritis
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Note: Prevalence of CagA and VacA Antibodies in Children with Helicobacter pylori-Associated Peptic Ulcer Compared to Prevalence in Pediatric Patients with Active or Nonactive Chronic Gastritis

机译:注意:幽门螺杆菌相关性消化性溃疡患儿中CagA和VacA抗体的患病率与小儿活动性或非活动性慢性胃炎患者的患病率相比

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摘要

VacA and CagA serological responses were detected in pediatric patients: 44 and 56%, respectively, in peptic ulcer (PU) patients, 33.3 and 44.4% in active chronic gastritis (ACG) patients, and 23.2 and 39.2% in non-ACG patients. Higher seroprevalence to CagA+VacA and to CagA+VacA+35-kDa antigen was found among PU patients. However, a low level of sensitivity and specificity was found for indirect detection of PU patients.
机译:在儿科患者中检测到VacA和CagA血清学应答:消化性溃疡(PU)患者分别为44%和56%,活动性慢性胃炎(ACG)患者分别为33.3和44.4%,非ACG患者为23.2和39.2%。在PU患者中发现CagA + VacA和CagA + VacA + 35-kDa抗原的血清阳性率较高。但是,发现间接检测PU患者的敏感性和特异性较低。

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