Prevalence of CagA and VacA Antibodies in Children with Helicobacter pylori-Associated Peptic Ulcer Compared to Prevalence in Pediatric Patients with Active or Nonactive Chronic Gastritis

T. Alarcón; M. J. Martínez; P. Urruzuno; M. L. Cilleruelo; D. Madruga; M. Sebastian

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Prevalence of CagA and VacA Antibodies in Children with Helicobacter pylori-Associated Peptic Ulcer Compared to Prevalence in Pediatric Patients with Active or Nonactive Chronic Gastritis

机译：幽门螺杆菌相关性消化性溃疡患儿中CagA和VacA抗体的患病率与小儿活动性或非活动性慢性胃炎患者的患病率相比

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VacA and CagA serological responses were detected in pediatric patients: 44 and 56%, respectively, in peptic ulcer (PU) patients, 33.3 and 44.4% in active chronic gastritis (ACG) patients, and 23.2 and 39.2% in non-ACG patients. Higher seroprevalence to CagA+VacA and to CagA+VacA+35-kDa antigen was found among PU patients. However, a low level of sensitivity and specificity was found for indirect detection of PU patients.

机译：在儿科患者中检测到VacA和CagA血清学应答：消化性溃疡（PU）患者分别为44％和56％，活动性慢性胃炎（ACG）患者分别为33.3和44.4％，非ACG患者为23.2和39.2％。在PU患者中，发现对CagA + VacA和CagA + VacA + 35-kDa抗原的血清阳性率较高。但是，发现间接检测PU患者的敏感性和特异性较低。

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《Clinical and diagnostic laboratory immunology》 |2000年第5期|共3页
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T. Alarcón; M. J. Martínez; P. Urruzuno; M. L. Cilleruelo; D. Madruga; M. Sebastian;
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1. Equally high prevalences of infection with cagA-positive Helicobacter pylori in Chinese patients with peptic ulcer disease and those with chronic gastritis-associated dyspepsia. [J] . Z J Pan, R W van der Hulst, M Feller, Journal of Clinical Microbiology . 1997,第6期

机译：在中国患有消化性溃疡疾病的患者和患有慢性胃炎相关消化不良的患者中，cagA阳性幽门螺杆菌感染的患病率同等高。
2. Prevalence of cagA and vacA genotypes of Helicobacter pylori isolated from Turkish patients with active or non-active chronic gastritis. [J] . Safak B, Ciftci IH, Dilek FH, Scandinavian journal of infectious diseases. . 2010,第6a7期

机译：从活跃或不活跃的慢性胃炎的土耳其患者中分离出幽门螺杆菌的cagA和vacA基因型的患病率。
3. Prevalence of hopQ Alleles and Relationship between cagA and vacA si with hopQ I Gene in Helicobacter pylori Strains Isolated from Patients with Peptic Ulcer Referred to Towhid Hospital in Sanandaj (2014) [J] . Amin Hooshyar Chichaklu, Manouchehr Ahmadi Hedayati, Farshad Sheykh Esmaili, Biosciences Biotechnology Research Asia . 2016,第1期

机译：从Sanandaj Towhid医院转诊的消化性溃疡患者中分离出的幽门螺杆菌菌株中hopQ等位基因的流行率以及cagA和vacA si与hopQ I基因的关系（2014）
4. Note: Prevalence of CagA and VacA Antibodies in Children with Helicobacter pylori-Associated Peptic Ulcer Compared to Prevalence in Pediatric Patients with Active or Nonactive Chronic Gastritis [O] . T. Alarcón, M. J. Martínez, P. Urruzuno, 2000

机译：注意：幽门螺杆菌相关性消化性溃疡患儿中CagA和VacA抗体的患病率与小儿活动性或非活动性慢性胃炎患者的患病率相比
5. Prevalence of hopQ Alleles and Relationship between cagA and vacA s1 with hopQ I Gene in Helicobacter pylori Strains Isolated from Patients with Peptic Ulcer Referred to Towhid Hospital in Sanandaj (2014) [O] . Amin Chichaklu, Manouchehr Hedayati, Farshad Esmaili, 2016

机译：嗜血杆菌菌株在幽门螺杆菌菌株中嗜血杆菌和Vaca s1与幽门螺杆菌菌株中的嗜血杆菌菌株的关系患病率分离出来的嗜血杆菌菌株患者，患有消化性溃疡患者，Sanandaj（2014年）

Prevalence of CagA and VacA Antibodies in Children with Helicobacter pylori-Associated Peptic Ulcer Compared to Prevalence in Pediatric Patients with Active or Nonactive Chronic Gastritis

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