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Applicability and significance of salicylate screening in sera of voluntary blood donors: evaluation of two analytical methods.

机译：水杨酸盐筛查在自愿献血者血清中的适用性和意义：两种分析方法的评估。

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摘要

Salicylate concentrations in 3819 sera of apparently healthy voluntary blood donors were determined in view of the significance of this drug in the induction of allergic reactions and its possible interference in platelet function. Two hundred and ninety-five sera were found by a modified colorimetric determination to contain salicylates. The colorimetric determination was compared with a high performance liquid chromatography (HPLC) analysis of salicylate-containing sera. Drug concentrations detected were mostly in the range of 20-100 mg/l. Such concentrations have been reported to evoke allergic reactions and to affect the haemostatic action of platelets.

机译：考虑到该药物在诱导过敏反应及其可能干扰血小板功能方面的重要性，确定了表面上健康的自愿献血者的3819血清中的水杨酸盐浓度。通过改进的比色法测定发现了295个血清中含有水杨酸盐。比色法测定与含水杨酸酯的血清的高效液相色谱（HPLC）分析进行比较。检测到的药物浓度大多在20-100 mg / l的范围内。据报道这种浓度会引起过敏反应并影响血小板的止血作用。

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期刊名称 Clinical Molecular Pathology
作者
R Sharon; I Frutkoff; G Kidroni; J Menczel;
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作者单位

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年(卷),期 1982(35),1
年度 1982
页码 59–62
总页数 4
原文格式 PDF
正文语种
中图分类病理学;
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7. Applicability and significance of salicylate screening in sera of voluntary blood donors: evaluation of two analytical methods. [O] . Sharon, R, Frutkoff, I, Kidroni, G, 1982

机译：水杨酸盐筛查在自愿献血者血清中的适用性和意义：两种分析方法的评估。
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Applicability and significance of salicylate screening in sera of voluntary blood donors: evaluation of two analytical methods.

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