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首页> 美国卫生研究院文献>International Journal of Clinical and Experimental Medicine >Puerarin injection for treatment of unstable angina pectoris: a meta-analysis and systematic review
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Puerarin injection for treatment of unstable angina pectoris: a meta-analysis and systematic review

机译：葛根素注射液治疗不稳定型心绞痛的Meta分析和系统评价

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摘要

Background: Puerarin is an effective ingredient isolated from Radix Puerariae, a leguminous plant. In China, a large number of early studies suggest that puerarin may be used in the treatment of coronary heart disease. In recent years, puerarin injection has been widely used to treat coronary heart disease and angina pectoris. Objective: To systematically evaluate the clinical efficacy and safety of puerarin injection in the treatment of unstable angina pectoris (UAP). Methods: Data were retrieved from digital databases, including PubMed, Excerpt Medica Database (EMBASE), China Biology Medicine (CBM), the Cochrane Library, and Chinese databases. Results: Compared with patients who were treated with conventional Western medicines alone, the patients who were treated with conventional Western medicines in combination with puerarin injection exhibited significant improvements in the incidence of angina pectoris, electrocardiogram findings, nitroglycerin consumption and plasma endothelin levels. Conclusions: Strong evidence suggests that, the use of puerarin in combination with conventional Western medicines is a better treatment option for treating UAP, compared with the use of conventional Western medicines alone.
机译：背景：葛根素是从豆科植物葛根中提取的有效成分。在中国，大量的早期研究表明，葛根素可用于治疗冠心病。近年来，葛根素注射液已被广泛用于治疗冠心病和心绞痛。目的：系统评价葛根素注射液治疗不稳定型心绞痛的临床疗效和安全性。方法：从数字数据库检索数据，包括PubMed，摘录医学数据库（EMBASE），中国生物医学（CBM），Cochrane图书馆和中文数据库。结果：与单独使用常规西药治疗的患者相比，使用常规西药联合葛根素注射治疗的患者在心绞痛的发生率，心电图检查结果，硝酸甘油消耗和血浆内皮素水平方面均表现出显着改善。结论：有力的证据表明，与单独使用常规西药相比，葛根素与常规西药结合使用是治疗UAP的更好治疗选择。

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