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首页> 美国卫生研究院文献>Materials >Physical Properties of PDMS (Polydimethylsiloxane) Microfluidic Devices on Fluid Behaviors: Various Diameters and Shapes of Periodically-Embedded Microstructures
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Physical Properties of PDMS (Polydimethylsiloxane) Microfluidic Devices on Fluid Behaviors: Various Diameters and Shapes of Periodically-Embedded Microstructures

机译：PDMS（聚二甲基硅氧烷）微流体装置在流体行为方面的物理特性：各种直径和周期性嵌入的微结构的形状

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摘要

Deformable polydimethylsiloxane (PDMS) microfluidic devices embedded with three differently-shaped obstacles (hexagon, square, and triangle) were used to examine the significant challenge to classical fluid dynamics. The significant factors in determining a quasi-steady state value of flow velocity (v)QS and pressure drop per unit length (∆P/∆x)QS were dependent on the characteristic of embedded microstructures as well as the applied flow rates. The deviation from the theoretical considerations due to PDMS bulging investigated by the friction constant and the normalized friction factor revealed that the largest PDMS bulging observed in hexagonal obstacles had the smallest (∆P/∆x)QS ratios, whereas triangle obstacles exhibited the smallest PDMS bulging, but recorded the largest (∆P/∆x)QS ratios. However, the influence of (v)QS ratio on microstructures was not very significant in this study. The results were close to the predicted values even though some discrepancy may be due to the relatively mean bulging and experimental uncertainty. The influence of deformable PDMS microfluidic channels with various shapes of embedded microstructures was compared with the rigid microchannels. The significant deviation from the classical relation (i.e., f~1/Re) was also observed in hexagonal obstacles and strongly dependent on the channel geometry, the degree of PDMS deformation, and the shapes of the embedded microstructures.
机译：嵌入了三个不同形状的障碍物（六边形，正方形和三角形）的可变形聚二甲基硅氧烷（PDMS）微流体装置用于研究对经典流体动力学的重大挑战。确定流速（v）QS和单位长度压降（ΔP/Δx）QS的准稳态值的重要因素取决于嵌入式微结构的特性以及所应用的流速。通过摩擦常数和归一化摩擦系数研究的PDMS凸起导致的理论考虑偏离表明，在六边形障碍物中观察到的最大PDMS凸起具有最小的（ΔP/Δx）QS比，而三角形障碍物表现出最小的PDMS凸起，但记录到最大的（QP /Δx）QS比。但是，（v）QS比对微观结构的影响在这项研究中不是很明显。即使有些差异可能是由于相对平均的凸起和实验不确定性，结果仍接近于预测值。比较了具有各种形状的嵌入式微结构的可变形PDMS微流体通道与刚性微通道的影响。在六角形障碍物中也观察到与经典关系的显着偏离（即f〜1 / Re），并且强烈依赖于通道的几何形状，PDMS变形的程度以及嵌入的微结构的形状。

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