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Reduction in peripheral blood K cells and activated T cells in primary biliary cirrhosis.

机译:原发性胆汁性肝硬化患者外周血K细胞和活化T细胞的减少。

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摘要

Lymphocyte subpopulations were measured in the peripheral blood of 13 patients with primary biliary cirrhosis (PBC), 13 with chronic active hepatitis (CAH), and 16 age- and sex-matched normal subjects. A significant, relative and absolute, reduction in activated T cells and K cells, compared with that in normal subjects, was found in PBC but not in CAH. The reduction in K cells observed in PBC was found to be accompanied by a parallel decrease in lymphocyte-mediated antibody-dependent cytotoxicity.
机译:在13例原发性胆汁性肝硬化(PBC),13例慢性活动性肝炎(CAH)和16例年龄和性别相匹配的正常受试者的外周血中测量了淋巴细胞亚群。与正常受试者相比,在正常人中发现活化的T细胞和K细胞有明显,相对和绝对的减少,而在CAH中则没有。发现在PBC中观察到的K细胞减少伴随着淋巴细胞介导的抗体依赖性细胞毒性的平行降低。

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