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Somatostatin and somatostatin analogues--are they indicated in the management of acute pancreatitis?

机译:生长抑素和生长抑素类似物-在急性胰腺炎的治疗中是否有指示?

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摘要

Somatostatin was first suggested for the treatment of acute pancreatitis more than 15 years ago but despite many studies, its role in the management of this condition remains unclear. The experimental and clinical studies are reviewed and the physiological actions of somatostatin, which may influence the course of acute pancreatitis are examined. It is concluded that although some reports suggest a trend towards improved survival and lessened complication rate with somatostatin treatment, insufficient evidence of benefit exists to support the use of somatostatin or its analogue in the treatment or prophylaxis against acute pancreatitis in routine clinical practice.
机译:生长抑素最早在15年前就被建议用于治疗急性胰腺炎,但是尽管有许多研究,其在控制这种疾病中的作用仍不清楚。审查了实验和临床研究,并研究了生长抑素可能影响急性胰腺炎病程的生理作用。结论是,尽管一些报道表明生长抑素治疗有改善生存率和降低并发症发生率的趋势,但尚无足够的获益证据支持生长抑素或其类似物在常规临床实践中用于治疗或预防急性胰腺炎。

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