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Proliferation of Hepatic Oval Cells via Cyclooxygenase-2 and Extracellular Matrix Protein Signaling during Liver Regeneration Following 2-AAF/Partial Hepatectomy in Rats

机译：大鼠2-AAF /部分肝切除术后肝再生期间通过环氧合酶-2和细胞外基质蛋白信号传导的肝卵圆形细胞的增殖。

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Background/AimsIn the 2-acetylaminofluorene (2-AAF)/70% partial hepatectomy (PHx) model, the mechanism underlying the differentiation of activated hepatic oval cells (HOCs) into hepatocytes and bile ductile cells is unclear. We investigated the role of cyclooxygenase-2 (COX-2) in HOCs and the relationship between COX-2 and extracellular matrix proteins in cellular proliferation.

机译：背景/目的在2-乙酰氨基芴（2-AAF）/ 70％部分肝切除术（PHx）模型中，激活的肝卵圆形细胞（HOC）分化为肝细胞和胆管韧性细胞的机制尚不清楚。我们调查了环氧合酶2（COX-2）在HOC中的作用以及COX-2和细胞外基质蛋白在细胞增殖中的关系。

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期刊名称 Gut and Liver
作者
Si Hyun Bae; Seh Hoon Oh; Seung Kew Yoon; Joung Ah Park; Gi Dae Kim; Wonhee Hur; Jong Young Choi; Il Hoan Oh; Kun Ho Yoon;
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作者单位

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年(卷),期 2011(5),3
年度 2011
页码 367–376
总页数 10
原文格式 PDF
正文语种
中图分类肠道病毒与肝炎病毒;肝及胆疾病;肠疾病;
关键词
Hepatic oval cells Cyclooxygenase-2 Liver generation;

机译：肝卵圆形细胞;环氧合酶-2;肝生成;

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专利

1. Proliferation of Hepatic Oval Cells via Cyclooxygenase-2 and Extracellular Matrix Protein Signaling during Liver Regeneration Following 2-AAF/Partial Hepatectomy in Rats [J] . Si Hyun Bae, Seh Hoon Oh, Seung Kew Yoon, Gut and Liver . 2011,第3期

机译：大鼠2-AAF /部分肝切除术后肝再生期间通过环氧合酶-2和细胞外基质蛋白信号传导的肝卵圆形细胞的增殖。
2. Hepatic non-parenchymal cells and extracellular matrix participate in oval cell-mediated liver regeneration. [J] . Zhang W, Chen XP, Zhang WG, World journal of gastroenterology : . 2009,第5期

机译：肝非实质细胞和细胞外基质参与卵圆细胞介导的肝再生。
3. Induction and contribution of beta platelet-derived growth factor signalling by hepatic stellate cells to liver regeneration after partial hepatectomy in mice [J] . Kocabayoglu Peri, Zhang David Y., Kojima Kensuke, Liver international : . 2016,第6期

机译：肝星状细胞诱导β-血小板衍生生长因子信号转导及对小鼠部分肝切除术后肝脏再生的贡献
4. Extracellular matrix proteins regulate Adipose Derived Mesenchymal Stem Cells and Amniotk Fluid Stem Cells attachment and proliferation: utility for tissue and organ regeneration [C] . Anna Bajek, Joanna Olkowska, Natalia Gurtowska, European conference on biomaterials . 2014

机译：细胞外基质蛋白调节脂肪来源的间充质干细胞和羊膜液干细胞的附着和增殖：用于组织和器官再生
5. The role of connective tissue growth factor (CTGF) in oval cell aided liver regeneration in the 2-AAF/PHx model. [D] . Pi, Liya. 2005

机译：在2-AAF / PHx模型中，结缔组织生长因子（CTGF）在卵圆细胞辅助肝再生中的作用。
6. Oval Cell Response Is Attenuated by Depletion of Liver Resident Macrophages in the 2-AAF/Partial Hepatectomy Rat [O] . Shuai Xiang, Han-Hua Dong, Hui-Fang Liang, 2009

机译：2-AAF /部分肝切除术大鼠肝脏中巨噬细胞耗竭可减轻卵圆细胞反应。
7. Proliferation of Hepatic Oval Cells via Cyclooxygenase-2 and Extracellular Matrix Protein Signaling during Liver Regeneration Following 2-AAF/Partial Hepatectomy in Rats [O] . Bae, Si Hyun, Oh, Seh Hoon, Yoon, Seung Kew, 2011

机译：大鼠2-AAF /部分肝切除术后肝再生期间通过环氧合酶-2和细胞外基质蛋白信号传导的肝卵圆形细胞的增殖

Proliferation of Hepatic Oval Cells via Cyclooxygenase-2 and Extracellular Matrix Protein Signaling during Liver Regeneration Following 2-AAF/Partial Hepatectomy in Rats

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