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首页> 美国卫生研究院文献>Gastroenterology Research and Practice >The Utility of Capsule Endoscopy in Patients under 50 Years of Age with Recurrent Iron Deficiency Anaemia: Is the Juice Worth the Squeeze?
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The Utility of Capsule Endoscopy in Patients under 50 Years of Age with Recurrent Iron Deficiency Anaemia: Is the Juice Worth the Squeeze?

机译：胶囊内窥镜检查在50岁以下反复缺铁性贫血患者中的作用：果汁值得吗？

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Background and Aims. The role of capsule endoscopy (CE) in the <50 years of age patients with iron deficiency anaemia (IDA) remains unclear. We aim to assess its utility in this cohort. Methods. All patients referred for CE for recurrent IDA were included retrospectively. Patients were divided into Group 1 (<50 years) and Group 2 (≥50 years). Results. There were 971 patients with recurrent IDA and 28% belonged to Group 1. The mean age was 40 years in this group with a DY of 28% (n = 76). Significant diagnoses included erosions and ulcers (26%; n = 71), small bowel (SB) angioectasia (AE) (10%; n = 27), SB tumours (3%; n = 7), Crohn's disease (3%; n = 7), SB bowel strictures (1%; n = 3), and SB varices (1%; n = 2). On logistic regression, the presence of diabetes (P = 0.02) and the use of warfarin (P = 0.049) was associated with increased DY. The DY in Group 2 was 38% which was significantly higher than in Group 1 (P = 0.02). While SB tumours were equally common in both groups, AE was commoner in Group 2 (P < 0.001). Conclusion. A significant proportion of patients <50 years are referred for CE. Although the DY is lower compared to those ≥50 years, significant pathology is found in this age group. CE is advisable in patients <50 years old with recurrent IDA and negative bidirectional endoscopies.
机译：背景和目标。 <50岁的铁缺乏性贫血（IDA）患者中胶囊内镜（CE）的作用尚不清楚。我们旨在评估其在这一队列中的效用。方法。回顾性纳入所有因复发IDA而接受CE治疗的患者。将患者分为1组（<50岁）和2组（≥50岁）。结果。有971例IDA复发患者，其中28％属于第1组。该组的平均年龄为40岁，DY为28％（n = 76）。重大诊断包括糜烂和溃疡（26％； n = 71），小肠（SB）血管扩张（AE）（10％； n = 27），SB肿瘤（3％； n = 7），克罗恩病（3％； n = 7），SB肠狭窄（1％； n = 3）和SB静脉曲张（1％； n = 2）。 Logistic回归分析显示，糖尿病（P = 0.02）和使用华法林（P = 0.049）与DY增加有关。第2组的DY为38％，明显高于第1组（P = 0.02）。尽管SB肿瘤在两组中均相同，但AE在第二组中更为常见（P <0.001）。结论。大部分<50岁的患者转为CE。尽管与50岁以上的人群相比DY较低，但在该年龄组中发现了明显的病理。小于50岁的IDA复发且双向内镜检查阴性的患者建议使用CE。

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