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首页> 美国卫生研究院文献>Frontiers in Pediatrics >Attrition in the European Child Cohort IDEFICS/I.Family: Exploring Associations Between Attrition and Body Mass Index
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Attrition in the European Child Cohort IDEFICS/I.Family: Exploring Associations Between Attrition and Body Mass Index

机译：欧洲儿童队列的减员IDEFICS / I.Family：探索减员与体重指数之间的关联

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Attrition may lead to bias in epidemiological cohorts, since participants who are healthier and have a higher social position are less likely to drop out. We investigated possible selection effects regarding key exposures and outcomes in the IDEFICS/I.Family study, a large European cohort on the etiology of overweight, obesity and related disorders during childhood and adulthood. We applied multilevel logistic regression to investigate associations of attrition with sociodemographic variables, weight status, and study compliance and assessed attrition across time regarding children's weight status and variations of attrition across participating countries. We investigated selection effects with regard to social position, adherence to key messages concerning a healthy lifestyle, and children's weight status. Attrition was associated with a higher weight status of children, lower children's study compliance, older age, lower parental education, and parent's migration background, consistent across time and participating countries. Although overweight (odds ratio 1.17, 99% confidence interval 1.05–1.29) or obese children (odds ratio 1.18, 99% confidence interval 1.03–1.36) were more prone to drop-out, attrition only seemed to slightly distort the distribution of children's BMI at the upper tail. Restricting the sample to subgroups with different attrition characteristics only marginally affected exposure-outcome associations. Our results suggest that IDEFICS/I.Family provides valid estimates of relations between socio-economic position, health-related behaviors, and weight status.
机译：减员可能会导致流行病学人群的偏见，因为更健康，社会地位较高的参与者辍学的可能性较小。我们在IDEFICS / I.Family研究中调查了有关关键暴露和结局的可能选择效果，该研究是欧洲大型队列研究，涉及儿童和成人期超重，肥胖及相关疾病的病因。我们应用了多级Logistic回归研究了社会人口统计学变量，体重状况与减员的关联，并研究了服从情况，并评估了各个年龄段儿童在参与国中儿童的体重状况和减员变化的减员情况。我们调查了选择效果，包括社会地位，对健康生活方式的关键信息的依从性以及儿童的体重状况。减员与儿童较高的体重状况，较低的儿童学习依从性，较低的年龄，较低的父母教育程度以及父母的迁徙背景有关，在各个时间段和参与国家中都保持一致。尽管超重（比值1.17，99％的置信区间1.05–1.29）或肥胖儿童（比值1.18，99％的置信区间1.03–1.36）更容易辍学，但减员似乎只会使儿童BMI的分布稍微失真在上尾巴。将样本限制为具有不同损耗特征的亚组，仅会稍微影响暴露结果关联。我们的结果表明，IDEFICS / I.Family提供了社会经济地位，健康相关行为与体重状况之间关系的有效估计。

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