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首页> 美国卫生研究院文献>Frontiers in Human Neuroscience >Interference Conditions of the Reconsolidation Process in Humans: The Role of Valence and Different Memory Systems
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Interference Conditions of the Reconsolidation Process in Humans: The Role of Valence and Different Memory Systems

机译：人在整合过程中的干扰条件：价和不同记忆系统的作用

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Following the presentation of a reminder, consolidated memories become reactivated followed by a process of re-stabilization, which is referred to as reconsolidation. The most common behavioral tool used to reveal this process is interference produced by new learning shortly after memory reactivation. Memory interference is defined as a decrease in memory retrieval, the effect is generated when new information impairs an acquired memory. In general, the target memory and the interference task used are the same. Here we investigated how different memory systems and/or their valence could produce memory reconsolidation interference. We showed that a reactivated neutral declarative memory could be interfered by new learning of a different neutral declarative memory. Then, we revealed that an aversive implicit memory could be interfered by the presentation of a reminder followed by a threatening social event. Finally, we showed that the reconsolidation of a neutral declarative memory is unaffected by the acquisition of an aversive implicit memory and conversely, this memory remains intact when the neutral declarative memory is used as interference. These results suggest that the interference of memory reconsolidation is effective when two task rely on the same memory system or both evoke negative valence.
机译：出现提示后，合并的内存将重新激活，然后进行重新稳定化的过程，这称为重新合并。用来揭示此过程的最常见的行为工具是在内存重新激活后不久由新学习产生的干扰。内存干扰定义为内存检索的减少，当新信息损害获取的内存时会产生这种影响。通常，目标内存和使用的干扰任务是相同的。在这里，我们研究了不同的内存系统和/或其价数如何产生内存重组干扰。我们表明，重新激活的中性声明性记忆可能会受到新的不同中性声明性记忆的学习的干扰。然后，我们揭示了令人厌恶的隐式记忆可能会受到提示的提示和紧随其后的威胁性社交事件的干扰。最后，我们表明，中性声明性内存的重组不受厌恶隐式内存的获取的影响，相反，当中性声明性内存用作干扰时，该内存保持不变。这些结果表明，当两个任务依赖于相同的内存系统或两者都引起负价时，内存重组的干扰是有效的。

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