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首页> 美国卫生研究院文献>Evidence-based Complementary and Alternative Medicine : eCAM >Jatropha gossypiifolia L. (Euphorbiaceae): A Review of Traditional Uses Phytochemistry Pharmacology and Toxicology of This Medicinal Plant
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Jatropha gossypiifolia L. (Euphorbiaceae): A Review of Traditional Uses Phytochemistry Pharmacology and Toxicology of This Medicinal Plant

机译：麻风树（大叶菊科）：该药用植物的传统用途植物化学药理学和毒理学概述

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摘要

Jatropha gossypiifolia L. (Euphorbiaceae), widely known as “bellyache bush,” is a medicinal plant largely used throughout Africa and America. Several human and veterinary uses in traditional medicine are described for different parts and preparations based on this plant. However, critical reviews discussing emphatically its medicinal value are missing. This review aims to provide an up-to-date overview of the traditional uses, as well as the phytochemistry, pharmacology, and toxicity data of J. gossypiifolia species, in view of discussing its medicinal value and potential application in complementary and alternative medicine. Pharmacological studies have demonstrated significant action of different extracts and/or isolated compounds as antimicrobial, anti-inflammatory, antidiarrheal, antihypertensive, and anticancer agents, among others, supporting some of its popular uses. No clinical trial has been detected to date. Further studies are necessary to assay important folk uses, as well as to find new bioactive molecules with pharmacological relevance based on the popular claims. Toxicological studies associated with phytochemical analysis are important to understand the eventual toxic effects that could reduce its medicinal value. The present review provides insights for future research aiming for both ethnopharmacological validation of its popular use and its exploration as a new source of herbal drugs and/or bioactive natural products.
机译：麻风树麻风树（Euphorbiaceae），被广泛称为“ bellyache bush”，是一种在非洲和美洲广泛使用的药用植物。描述了基于该植物的不同部位和制剂在传统医学中的几种人畜兽用。但是，缺少强调讨论其药用价值的评论。这篇综述旨在讨论棉铃虫种的传统用途以及其化学价值，药理学和毒性数据，以期探讨其药用价值以及在补充和替代医学中的潜在应用。药理研究表明，不同的提取物和/或分离出的化合物具有显著作用，例如抗微生物剂，抗炎剂，止泻药，降压药和抗癌药等，从而支持了其一些流行用途。迄今为止尚未检测到临床试验。有必要进行进一步的研究以测定重要的民间用途，并根据流行的说法找到具有药理学意义的新生物活性分子。与植物化学分析相关的毒理学研究对于了解最终的毒性作用可能会降低其药用价值非常重要。本综述为未来的研究提供了见识，旨在对其民族用途进行民族药理学验证，并探索其作为草药和/或生物活性天然产物的新来源。

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