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首页> 美国卫生研究院文献>Evidence-based Complementary and Alternative Medicine : eCAM >Relationship between Biomechanical Characteristics of Spinal Manipulation and Neural Responses in an Animal Model: Effect of Linear Control of Thrust Displacement versus Force Thrust Amplitude Thrust Duration and Thrust Rate
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Relationship between Biomechanical Characteristics of Spinal Manipulation and Neural Responses in an Animal Model: Effect of Linear Control of Thrust Displacement versus Force Thrust Amplitude Thrust Duration and Thrust Rate

机译：脊髓操纵的生物力学特征与动物模型中神经反应之间的关系：推力位移与力推力幅度推力持续时间和推力速率的线性控制的影响

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摘要

High velocity low amplitude spinal manipulation (HVLA-SM) is used frequently to treat musculoskeletal complaints. Little is known about the intervention's biomechanical characteristics that determine its clinical benefit. Using an animal preparation, we determined how neural activity from lumbar muscle spindles during a lumbar HVLA-SM is affected by the type of thrust control and by the thrust's amplitude, duration, and rate. A mechanical device was used to apply a linear increase in thrust displacement or force and to control thrust duration. Under displacement control, neural responses during the HVLA-SM increased in a fashion graded with thrust amplitude. Under force control neural responses were similar regardless of the thrust amplitude. Decreasing thrust durations at all thrust amplitudes except the smallest thrust displacement had an overall significant effect on increasing muscle spindle activity during the HVLA-SMs. Under force control, spindle responses specifically and significantly increased between thrust durations of 75 and 150 ms suggesting the presence of a threshold value. Thrust velocities greater than 20–30 mm/s and thrust rates greater than 300 N/s tended to maximize the spindle responses. This study provides a basis for considering biomechanical characteristics of an HVLA-SM that should be measured and reported in clinical efficacy studies to help define effective clinical dosages.
机译：高速低振幅脊柱操纵（HVLA-SM）经常用于治疗肌肉骨骼疾病。决定其临床获益的干预措施的生物力学特性知之甚少。通过动物准备，我们确定了在腰部HVLA-SM期间来自腰肌纺锤体的神经活动如何受到推力控制类型以及推力幅度，持续时间和速率的影响。使用机械装置施加推力位移或力的线性增加并控制推力持续时间。在位移控制下，HVLA-SM期间的神经反应以推力幅度分级的方式增加。在力控制下，无论推力幅度如何，神经反应都是相似的。除最小推力位移外，在所有推力幅度上减小推力持续时间对HVLA-SM期间增加的肌肉纺锤活动具有总体显着影响。在力控制下，主轴响应在推力持续时间75到150µms之间特别显着增加，这表明存在阈值。推力速度大于20–30 mm / s，推力速度大于300 N / s倾向于最大化主轴响应。这项研究为考虑HVLA-SM的生物力学特征提供了基础，应在临床疗效研究中对其进行测量和报告，以帮助确定有效的临床剂量。

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