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首页> 美国卫生研究院文献>European Journal of Human Genetics >Preferences for prenatal tests for Down syndrome: an international comparison of the views of pregnant women and health professionals
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Preferences for prenatal tests for Down syndrome: an international comparison of the views of pregnant women and health professionals

机译：唐氏综合症产前检查的偏爱：孕妇和卫生专业人员意见的国际比较

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摘要

Non-invasive prenatal testing is increasingly available worldwide and stakeholder viewpoints are essential to guide implementation. Here we compare the preferences of women and health professionals from nine different countries towards attributes of non-invasive and invasive prenatal tests for Down syndrome. A discrete choice experiment was used to obtain participants' stated preference for prenatal tests that varied according to four attributes: accuracy, time of test, risk of miscarriage, and type of information. Pregnant women and health professionals were recruited from Canada, Denmark, Iceland, Israel, Italy, the Netherlands, Portugal, Singapore, and the United Kingdom. A total of 2666 women's and 1245 health professionals' questionnaires were included in the analysis. Differences in preferences were seen between women and health professionals within and between countries. Overall, women placed greater emphasis on test safety and comprehensive information than health professionals, who emphasised accuracy and early testing. Differences between women's and health professionals' preferences are marked between countries. Varied approaches to implementation and service delivery are therefore needed and individual countries should develop guidelines appropriate for their own social and screening contexts.
机译：非侵入性产前检查在世界范围内越来越多，利益相关者的观点对于指导实施至关重要。在这里，我们比较了来自9个不同国家的女性和卫生专业人员对唐氏综合症的非侵入性和侵入性产前检查属性的偏好。使用离散选择实验获得参与者对产前检查的陈述性偏好，该偏好根据四个属性而变化：准确性，测试时间，流产风险和信息类型。从加拿大，丹麦，冰岛，以色列，意大利，荷兰，葡萄牙，新加坡和英国招募了孕妇和卫生专业人员。分析中总共包括2666名女性和1245名卫生专业人员的问卷。在国家内部和国家之间，妇女与卫生专业人员之间的偏好有所不同。总体而言，与健康专业人员相比，女性更加强调测试安全性和全面信息，后者强调准确性和早期测试。在国家之间，女性和卫生专业人员的偏好之间存在明显差异。因此，需要采用各种方法来实施和提供服务，并且各个国家应制定适合其自身社会和筛查背景的指南。

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