Development of a novel monoclonal antibody to B7-H4: characterization and biological activity

机译：抗B7-H4新型单克隆抗体的开发：表征和生物学活性

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摘要

ObjectiveB7-H4, a member of the B7 family of immunoregulatory receptors, may participate in the negative regulation of cell-mediated immunity. Aberrant B7-H4 expression is detected in some tumors and it plays a role in the occurrence and development of tumors. The aim of this study was to elucidate the functional and structural properties of B7-H4.

机译：ObjectiveB7-H4是免疫调节受体B7家族的成员，可能参与细胞介导的免疫的负调节。在一些肿瘤中检测到异常的B7-H4表达，它在肿瘤的发生和发展中起作用。这项研究的目的是阐明B7-H4的功能和结构特性。

著录项

期刊名称 European Journal of Medical Research
作者
Y Qian; L Shen; C Xu; Z Wu; NH Brockmeyer; P Altmeyer; N Wu; H Yao;
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作者单位

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年(卷),期 2011(16),7
年度 2011
页码 295–302
总页数 8
原文格式 PDF
正文语种
中图分类医学史;
关键词
B7-H4 monoclonal antibody immunologic techniques biological activity;

机译：B7-H4;单克隆抗体;免疫学技术;生物活性;

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专利

1. Development of a novel monoclonal antibody to B7-H4: characterization and biological activity. [J] . Qian Y, Shen L, Xu C, European journal of medical research. . 2011,第7期

机译：B7-H4新型单克隆抗体的开发：表征和生物学活性。
2. Development of a novel monoclonal antibody to B7-H4: characterization and biological activity [J] . Y Qian, L Shen, C Xu, European journal of medical research. . 2011,第7期

机译：新型针对B7-H4的单克隆抗体的开发：表征和生物学活性
3. Development of a Novel Functional Monoclonal Antibody to Human CD275: Characterization and Biological Activity [J] . JiangsuProvinceKeyLaboratoryofStemCellResearchSoochowUniversity, JiangsuInstituteofClinicalImmunologySoochowUniversity Monoclonal antibodies in immunodiagnosis and immunotherapy . 2016,第1期

机译：人类CD275的新型功能单克隆抗体的开发：表征和生物活性。
4. DEVELOPMENT OF MASS SPECTROMETRIC AND INFORMATICS WORKFLOWS FOR COMPREHENSIVE CHARACTERIZATION OF RECOMBINANT MONOCLONAL ANTIBODIES AND FUSION PROTEINS [C] . Jeremy Woods, Prathima Acharya, Weibin Chen, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2012

机译：基于重组单克隆抗体和融合蛋白的综合表征质谱和信息学工作流程
5. Characterization of Anti-Ricin Monoclonal Antibodies and the Construction of a Chimeric Murine-Human IgG2/K Anti-Ricin Monoclonal Antibody [D] . Vendramelli, Robert Matthew 2011

机译：抗蓖麻毒蛋白单克隆抗体的表征和鼠/人IgG2 / K嵌合抗蓖麻毒蛋白单克隆抗体的构建
6. Development characterization and biological properties of meningococcal immunotype L37(8)9-specific monoclonal antibodies. [O] . A F Verheul, A J Kuipers, A K Braat, 1994

机译：脑膜炎球菌免疫型L37（8）9特异性单克隆抗体的开发表征和生物学特性。
7. Development of a novel monoclonal antibody to B7-H4: characterization and biological activity [O] . Qian Y, Shen L, Xu C, 2011

机译：抗B7-H4新型单克隆抗体的开发：表征和生物学活性
8. Characterization of Monoclonal Antibodies that Inhibit the Catalytic Activity ofAcetylcholinesterases [R] . Gentry, M. K., Moorad, D. R., Hur, R. S., 1995

机译：表征抑制乙酰胆碱酯酶催化活性的单克隆抗体

Development of a novel monoclonal antibody to B7-H4: characterization and biological activity

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