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Expression and epigenomic landscape of the sex chromosomes in mouse post-meiotic male germ cells

机译：小鼠减数分裂后雄性生殖细胞中性染色体的表达和表观基因组学情况

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摘要

Background During meiosis, the X and Y chromosomes are transcriptionally silenced. The persistence of repressive chromatin marks on the sex chromatin after meiosis initially led to the assumption that XY gene silencing persists to some extent in spermatids. Considering the many reports of XY-linked genes expressed and needed in the post-meiotic phase of mouse spermatogenesis, it is still unclear whether or not the mouse sex chromatin is a repressive or permissive environment, after meiosis.

机译：背景在减数分裂期间，X和Y染色体在转录上被沉默。减数分裂后性染色质上抑制性染色质标记的持久性最初导致了这样一个假设，即在精子中XY基因沉默在某种程度上持续存在。考虑到在小鼠精子发生后减数分裂阶段表达和需要的XY连锁基因的许多报道，尚不清楚减数分裂后小鼠性染色质是抑制性还是允许性环境。

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期刊名称 Epigenetics Chromatin
作者
Charlotte Moretti; Daniel Vaiman; Frederic Tores; Julie Cocquet;
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作者单位

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年(卷),期 2016(9),-1
年度 2016
页码 47
总页数 18
原文格式 PDF
正文语种
中图分类遗传学;
关键词
Sex chromosomes Post-meiotic sex chromatin MSCI Spermiogenesis Mouse H3K4me3 Crotonylation H3K9me3 H3K27ac Chromosome 14;

机译：性染色体;减数分裂后的染色质;MSCI;生精;小鼠;H3K4me3;巴豆酰化;H3K9me3;H3K27ac;染色体14;

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专利

1. Expression and epigenomic landscape of the sex chromosomes in mouse post-meiotic male germ cells [J] . Charlotte Moretti, Daniel Vaiman, Frederic Tores, Epigenetics & Chromatin . 2016,第1期

机译：小鼠减数分裂后雄性生殖细胞中性染色体的表达及表观基因组学情况
2. Large, male germ cell-specific hypomethylated DNA domains with unique genomic and epigenomic features on the mouse X chromosome [J] . IkedaR., ShiuraH., NumataK., DNA research: an international journal for rapid publication of reports on genes and genomes . 2013,第6期

机译：大型男性生殖细胞特异性低甲基化DNA结构域，在小鼠X染色体上具有独特的基因组和表观基因组特征
3. Large, Male Germ Cell-Specific Hypomethylated DNA Domains With Unique Genomic and Epigenomic Features on the Mouse X Chromosome [J] . Hirosuke Shiura, John M. Greally, Koji Numata, DNA research: an international journal for rapid publication of reports on genes and genomes . 2013,第6期

机译：大型，男性生殖细胞特定的次甲基化的DNA域具有鼠标X染色体上独特的基因组和表观基因组特征。
4. Impact of WR-2721 on X-ray induced alterations in germ cells of male mouse [C] . Bhartiya, J., Bhartiya, . 1988

机译：WR-2721对X射线诱导的雄性小鼠生殖细胞改变的影响
5. Origin of DNA methylation patterns in the male germ line: Roles of the novel DNA methyltransferases in male germ cells. [D] . La Salle, Sophie. 2007

机译：雄性生殖系中DNA甲基化模式的起源：新型DNA甲基转移酶在雄性生殖细胞中的作用。
6. Editors choice: Large Male Germ Cell-Specific Hypomethylated DNA Domains With Unique Genomic and Epigenomic Features on the Mouse X Chromosome [O] . Rieko Ikeda, Hirosuke Shiura, Koji Numata, 2013

机译：编辑选择：在小鼠X染色体上具有独特的基因组和表观基因组特征的大型雄性生殖细胞特定的次甲基化DNA结构域
7. Expression and epigenomic landscape of the sex chromosomes in mouse post-meiotic male germ cells [O] . Charlotte Moretti, Daniel Vaiman, Frederic Tores, 2016

机译：小鼠减数分裂后雄性生殖细胞中性染色体的表达和表观基因组学情况
8. Stage-Specific Damage to Synaptonemal Complexes and Metaphase Chromosomes Inducedby X Rays in Male Mouse Germ Cells [R] . Backer, L. C., Sontag, M. R., Allen, J. W. 1991

机译：对雄性小鼠生殖细胞中X射线诱导的联会复合体和中期染色体的阶段特异性损伤

Expression and epigenomic landscape of the sex chromosomes in mouse post-meiotic male germ cells

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