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The antibiotic resistance patterns of Salmonella Typhi isolates in Italy 1980-96. The Italian SALM-NET Working Group. Salmonella Network.

机译:意大利伤寒沙门氏菌分离株的抗生素耐药性模式1980-96年。意大利SALM-NET工作组。沙门氏菌网络。

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摘要

In this paper we report the distribution of Salmonella Typhi isolates in Italy and their resistance patterns to antibiotics. The data were collected by the Italian SALM-NET surveillance system in a pilot retrospective study of the period 1980-96. Data on drug-resistance were available for 82 isolates out of 176 S. Typhi isolated in Italy. Of these 82 isolates, 32 (39%) were resistant or intermediate to 1 or more antibiotics. Eight isolates were resistant and 7 intermediate to streptomycin; 4 isolates were resistant to ampicillin alone or in association with other antibiotics; only 2 strains (1 isolated in Lombardia in 1993 and the other 1 in Lazio in 1994) were resistant to chloramphenicol, and 2 (isolated in Sardegna and Piemonte in 1995 and 1996, respectively) showed intermediate resistance to chloramphenicol. The strains showing resistance to 3 or more antibiotics were very scarce: 1 (with 5 complete resistances) was isolated in Lazio in 1994, and another 1 (with complete resistance to 10 antibiotics and intermediate resistance to 2 antibiotics) was isolated in Molise in 1988. In conclusion, besides the routine activities to control typhoid fever, an accurate and continuous surveillance is necessary in order to quickly identify multidrug-resistant (MDR) S. Typhi strains and prevent their spread, even though their level, in our country, is still quite low.
机译:在本文中,我们报告了伤寒沙门氏菌在意大利的分布及其对抗生素的耐药性。数据是由意大利SALM-NET监视系统在1980-96年期间进行的一项试点回顾研究中收集的。在意大利分离的176株伤寒沙门氏菌中,有82株分离物具有耐药性数据。在这82株分离株中,有32株(39%)对一种或多种抗生素具有抗药性或在其中。八株菌株对链霉素有抗药性,其中七株对链霉素有抗性。 4株单独或与其他抗生素联合使用对氨苄西林耐药;只有2株(对1993年在伦巴第大区分离,另外1对在1994年在拉齐奥分离)对氯霉素具有抗性,而2株(分别在1995年和1996年在Sardegna和Piemonte分离)对氯霉素具有中等抗性。对3种或3种以上抗生素具有抗药性的菌株非常稀少:1994年在拉齐奥分离出1种(具有5种完全抗药性),1988年在莫利塞分离出另一种1种(对10种抗生素具有完全抗药性,对2种抗生素具有中等抗性)总之,除了控制伤寒的常规活动外,准确,连续的监测是必要的,以便快速鉴定出耐多药性(MDR)的伤寒沙门氏菌菌株,并防止其扩散,即使其水平在我国是仍然很低。

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