首页> 美国卫生研究院文献>Diabetes Metabolism Journal >The Necessity of the Simple Tests for Diabetic Peripheral Neuropathy in Type 2 Diabetes Mellitus Patients without Neuropathic Symptoms in Clinical Practice
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The Necessity of the Simple Tests for Diabetic Peripheral Neuropathy in Type 2 Diabetes Mellitus Patients without Neuropathic Symptoms in Clinical Practice

机译:在临床实践中对没有神经病变症状的2型糖尿病患者进行糖尿病周围神经病变的简单检测的必要性

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摘要

Early recognition and appropriate management of diabetic peripheral polyneuropathy (DPNP) is important. We evaluated the necessity of simple, non-invasive tests for DPNP detection in clinical practice. We enrolled 136 randomly-chosen patients with type 2 diabetes mellitus and examined them with the 10-g Semmes-Weinstein monofilament examination, the 128-Hz tuning-fork, ankle-reflex, and pinprick tests; the Total Symptom Score and the 15-item self-administered questionnaire of the Michigan Neuropathy Screening Instrument. Among 136 patients, 48 had subjective neuropathic symptoms and 88 did not. The abnormal-response rates varied depending on the methods used according to the presence of subjective neuropathic symptoms (18.8% vs. 5.7%, P<0.05; 58.3% vs. 28.4%, P<0.005; 81.3% vs. 54.5%, P<0.005; 12.5% vs. 5.7%, P=0.195; 41.7% vs. 2.3%, P<0.001; and 77.1% vs. 9.1%, P<0.001; respectively). The largest abnormal response was derived by combining all methods. Moreover, these tests should be implemented more extensively in diabetic patients without neuropathic symptoms to detect DPNP early.
机译:糖尿病周边多发性神经病(DPNP)的早期识别和适当管理很重要。我们评估了在临床实践中进行DPNP检测的简单,非侵入性测试的必要性。我们招募了136名随机选择的2型糖尿病患者,并通过10 g Semmes-Weinstein单丝检查,128 Hz音叉,脚踝反射和针刺试验对其进行了检查。症状总评分和密歇根州神经病变筛查仪器的15个项自我管理问卷。在136例患者中,有48例具有主观神经病症状,而88例则没有。异常反应率因主观神经病症状的存在而异,取决于所使用的方法(18.8%vs. 5.7%,P <0.05; 58.3%vs. 28.4%,P <0.005; 81.3%vs.54.5%,P <0.005; 12.5%vs. 5.7%,P = 0.195; 41.7%vs. 2.3%,P <0.001;和77.1%vs. 9.1%,P <0.001;综合所有方法得出最大的异常反应。此外,这些检查应在没有神经病症状的糖尿病患者中更广泛地实施,以及早发现DPNP。

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