Clinical Importance of Somatostatin Receptor 2 (SSTR2) and Somatostatin Receptor 5 (SSTR5) Expression in Thyrotropin-Producing Pituitary Adenoma (TSHoma)

机译：生长激素抑制素垂体腺瘤（TSHoma）中生长抑素受体2（SSTR2）和生长抑素受体5（SSTR5）表达的临床重要性

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

BackgroundThyrotropin-secreting pituitary adenomas (TSHomas) are a rare cause of hyperthyroidism. Somatostatin analogs have proved to be effective for inhibiting pituitary hormones secretion, working via interactions with somatostatin receptors (SSTRs). Moreover, antiproliferative activity of somatostatin analog is now demonstrated in several studies. In the present study, we determined the relative predominance of SSTR2 and SSTR5 subtypes among the different types of adenomas, especially TSHoma, and investigated the relationship between efficacy of short-term octreotide (OCT) treatment and SSTR expression.

机译：背景促甲状腺激素分泌垂体腺瘤（TSHomas）是甲状腺机能亢进的罕见原因。生长抑素类似物通过与生长抑素受体（SSTR）的相互作用，被证明可有效抑制垂体激素分泌。而且，生长激素抑制素类似物的抗增殖活性现已在数项研究中得到证实。在本研究中，我们确定了不同类型的腺瘤（尤其是TSHoma）之间SSTR2和SSTR5亚型的相对优势，并研究了短期奥曲肽（OCT）疗效与SSTR表达之间的关系。

著录项

期刊名称 Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
作者
Benxia Yu; Zhongsheng Zhang; Hao Song; Yuchun Chi; Chunling Shi; Miao Xu;
展开▼
作者单位

展开▼
年(卷),期 2017(23),-1
年度 2017
页码 1947–1955
总页数 7
原文格式 PDF
正文语种
中图分类
关键词
ACTH-Secreting Pituitary Adenoma Growth Hormone-Secreting Pituitary Adenoma Immunohistochemistry;

机译：ACTH分泌型垂体腺瘤;生长激素分泌型垂体腺瘤;免疫组化;

相似文献

外文文献
中文文献
专利

1. Immunohistochemical expression of somatostatin receptors SSTR2A and SSTR5 in 299 pituitary adenomas [J] . Fuchs Talia L., Sioson Loretta, Sheen Amy, Pathology . 2018,第4期

机译：299例垂体腺瘤中生长抑制菌素受体SSTR2A和SSTR5的免疫组织化学表达
2. Protein expression of somatostatin receptor 2, somatostatin receptor 5 and dopamine D2 receptor in normal pituitary gland and ACTH-secreting pituitary adenoma in dogs [J] . Asaka Sato, Yasushi Hara Research in Veterinary Science . 2018,第期

机译：生长抑素受体2，生长抑素受体5和多巴胺D2受体在正常脑垂体中的蛋白质表达和犬犬分泌垂体腺瘤
3. Inhibition of cell proliferation by the somatostatin analogue RC-160 is mediated by somatostatin receptor subtypes SSTR2 and SSTR5 through different mechanisms. [J] . Buscail L, Esteve JP, Saint Laurent N, Proceedings of the National Academy of Sciences of the United States of America . 1995,第5期

机译：生长抑素类似物RC-160对细胞增殖的抑制作用是通过不同的机制由生长抑素受体亚型SSTR2和SSTR5介导的。
4. Novel Camptothecin Somatostatin Conjugate in Treatment of Tumor Cells Expressing sst2 Receptors [C] . Philip G. Kasprzyk, Ann V. Fiore, Yeelana Shen American Peptide Symposium . 2013

机译：新型Camptothecin Somatostatin缀合物治疗表达SST2受体的肿瘤细胞
5. Somatostatin Receptor Type 2 (SSTR2) for Adoptive T Cell Imaging, Stimulation, and Elimination [D] . Vedvyas, Yogindra. 2018

机译：对于采用T细胞成像，刺激和消除，生长抑素受体类型2（SSTR2）
6. Retracted: Clinical Importance of Somatostatin Receptor 2 (SSTR2) andSomatostatin Receptor 5 (SSTR5) Expression in Thyrotropin-Producing Pituitary Adenoma(TSHoma) [O] . Hao Song, Yuchun Chi, Chunling Shi, 1923

机译：缩回：生长抑素受体2（SSTR2）和生长抑素受体5（SSTR5）在促甲状腺素产生的垂体腺瘤中的表达。（TSHoma）
7. Somatostatin Receptor Subtype Specificity in Human Fetal Pituitary Cultures Differential Role of SSTR2 and SSTR5 for Growth Hormone, Thyroid-stimulating Hormone, and Prolactin Regulation [O] . J. Clin Invest, Ilan Shimon, John E. Taylor, 2016

机译：生长抑素受体亚型在人胎儿垂体细胞中的特异性ssTR2和ssTR5对生长激素，促甲状腺激素和催乳素调节的不同作用

Clinical Importance of Somatostatin Receptor 2 (SSTR2) and Somatostatin Receptor 5 (SSTR5) Expression in Thyrotropin-Producing Pituitary Adenoma (TSHoma)

摘要

著录项

相似文献

相关主题

期刊订阅