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首页> 美国卫生研究院文献>Molecules >Elicitation an Effective Strategy for the Biotechnological Production of Bioactive High-Added Value Compounds in Plant Cell Factories
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Elicitation an Effective Strategy for the Biotechnological Production of Bioactive High-Added Value Compounds in Plant Cell Factories

机译：启发植物细胞工厂中生物活性高附加值化合物的生物技术生产的有效策略

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摘要

Plant in vitro cultures represent an attractive and cost-effective alternative to classical approaches to plant secondary metabolite (PSM) production (the “Plant Cell Factory” concept). Among other advantages, they constitute the only sustainable and eco-friendly system to obtain complex chemical structures biosynthesized by rare or endangered plant species that resist domestication. For successful results, the biotechnological production of PSM requires an optimized system, for which elicitation has proved one of the most effective strategies. In plant cell cultures, an elicitor can be defined as a compound introduced in small concentrations to a living system to promote the biosynthesis of the target metabolite. Traditionally, elicitors have been classified in two types, abiotic or biotic, according to their chemical nature and exogenous or endogenous origin, and notably include yeast extract, methyl jasmonate, salicylic acid, vanadyl sulphate and chitosan. In this review, we summarize the enhancing effects of elicitors on the production of high-added value plant compounds such as taxanes, ginsenosides, aryltetralin lignans and other types of polyphenols, focusing particularly on the use of a new generation of elicitors such as coronatine and cyclodextrins.
机译：植物体外培养是生产植物次生代谢产物（PSM）的经典方法（“植物细胞工厂”概念）的一种有吸引力且具有成本效益的替代方法。除其他优势外，它们构成了唯一的可持续性和生态友好型系统，能够获得由抵抗驯化的稀有或濒危植物物种生物合成的复杂化学结构。为获得成功的结果，PSM的生物技术生产需要优化的系统，为此，诱变已被证明是最有效的策略之一。在植物细胞培养物中，引发剂可以定义为以低浓度引入到生命系统中以促进靶代谢物的生物合成的化合物。传统上，引发剂根据其化学性质和外源或内源起源被分为非生物或生物两种类型，特别包括酵母提取物，茉莉酸甲酯，水杨酸，硫酸氧钒和壳聚糖。在这篇综述中，我们总结了引发剂对生产高附加值植物化合物（如紫杉烷，人参皂甙，芳基四氢木脂木脂素和其他类型的多酚）的增强作用，尤其着重于新一代引发剂（如冠状花素和环糊精。

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